Background:
Patients on hemodialysis are at a high risk of psychiatric disorders as they
face an emotional challenge in addition to physical impairment.
Objective:
This study aims to assess the prevalence of depression and anxiety among a sample of
patients with end-stage renal disease on regular dialysis, and the effect of resilience and social support
on them.
Methods:
This cross-sectional study was conducted on 45 patients who had been on hemodialysis
for the past three months. Anxiety and depression were assessed with a clinical interview. The severity
of depression, perceived social support, and resilience were assessed using the Beck Depression
Inventory (BDI), Multi-dimensional Scale of Perceived Social Support (MSPSS), and Resilience
Scale, respectively.
Result:
The mean age of enrolled patients was 49.2 ± 14.0 years, and the mean duration of hemodialysis
was 4.5 ± 3.8 years. The prevalence of depression was 24.4% and that of anxiety was 20%.
According to our analysis, 15 (33.3%) patients were diagnosed with minor depression, 6 (13.3%)
with mild depression, 14 (31.1%) with moderate depression, and 10 (22.2%) with severe depression.
Resilience correlated significantly with a psychiatric diagnosis (p=0.004). Perceived social support
was also found to be significantly correlated with a psychiatric diagnosis (p=0.012).
Conclusion:
Depression and anxiety are common mental disorders in patients with CKD and are
considered as the main determinants of quality of life and death rate. Increasing awareness, early
evaluation, and management of depression and anxiety may improve the functional, social, and
clinical outcomes of the patients with CKD.
The current study was performed to investigate age-dependent immunoexpression and localization of somatotropin in the pituitary gland. Twenty adult Wistar rats (fifteen females and five males) were housed; four animals per cage with observation of pregnancy. Samples from pituitary gland were collected from different ages of male offsprings. Tissue specimens were processed, and stained with Hematoxylin and Eosin (H&E), special stain and immunohistochemical technique. Sections were divided into four stages. H&E results showed that at stage I, acidophils were the most distinguished cells; but basophils were difficult to be seen then appeared at stage II. Special stain results showed increasing in somatotrophs number from stage I to stage III then decreased at the last stage. Immunoexpression of somatotropin in pars distalis showed that somatotrophs were numerous and uniformly distributed at the first three stages then they were restricted in clusters at the last stage.
This study was conducted on nine heads of normal adult one‐humped camels. The specimens were collected from Cairo slaughterhouse. The nasal cavity in the freshly collected samples were dissected and photographed. The specimens for microscopic studies were fixed in different fixatives and prepared to examine by light and scanning electron microscope (SEM). The nasal cavity of the camel was studied grossly and by using of light and scanning electron microscope. Specimens from different regions of this cavity were subjected to different histological stains and also demonstrated by the acid and alkaline phosphatases. Gross morphological examination of this cavity showed its three parts: rostral part (the nasal vestibule) covered with skin of usual structure then it lined with smooth mucosa. The middle part (respiratory) had dorsal, middle and ventral nasal conchae, but the caudal part (olfactory) contained the ethmoidal concha. The lining mucosa of the camel nasal cavity was similar to that of other mammals, but there were some differences: the respiratory epithelium showed a small number of goblet cells and there were a mixture of acidic and neutral mucins inside the epithelial and glandular mucous cells. Strong acid and alkaline phosphatase reaction was observed in the lining epithelium of the nasal cavity. By SEM, it showed the surface epithelial layer of the nasal cavity mucosa in three regions (vestibule, respiratory and olfactory) and resulted that it was stratified cuboidal to columnar epithelium, ciliated pseudostratified columnar epithelium with few goblet cells or olfactory mucosa containing neurosensory olfactory cells. This study aimed to investigate the anatomical features, the histological and histochemical structures of the nasal cavity in one humped camel. The findings of this study were discussed with the previous works in this field with the other domestic animals.
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