Strongyloides stercoralis hyperinfection syndrome is classically associated with impaired host response and implies in an overburden of larvae in its usual cycle. It has been recognized as a severe and potentially fatal condition in immunocompromised individuals, especially those using oral corticosteroids. Infection with Schistosoma mansoni not only increases the susceptibility to HIV infection, but also promotes progression to disease. The association of the most severe forms of strongyloidiasis and AIDS is scarcely described, even more when S. mansoni is also associated. The authors describe a case of a 34-year-old previously healthy male, admitted to the emergency department with a history of hematemesis associated with dyspnea, hemoptysis, and fever. He referred homosexual relations for 6 years. Physical examination showed an ill-looking patient, and was remarkable for tachycardia, tachypnea, diaphoresis, and pulse oximetry of 70% in room air. Lungs examination revealed the presence of rales in the left base. Chest radiography showed a diffuse and bilateral reticulo-nodular pattern. HIV serology was positive. Empirical antimicrobial therapy and corticosteroids were initiated. On the third day of hospitalization, petechiae appeared over the periumbilical area, but no further investigation was undertaken because the patient died soon after. The autopsy findings were compatible with S. stercoralis disseminated infection, a hepatic intestinal chronic form of schistosomiasis, and septic shock as the primary cause of death. The authors call attention to this infrequent association.
ST-segment elevation, observed in the critically ill patients, almost always raises the suspicion of ischemic heart disease. However, nonischemic myocardial and non-myocardial problems in these patients may also lead to ST-segment elevation. Pneumothorax and pneumopericardium have been rarely reported as a cause of transient ST-segment elevation. The authors report the case of a patient admitted to the emergency care unit because of a respiratory failure requiring mechanical ventilatory support. As the patient showed signs of clinical deterioration, a pneumothorax was clinically diagnosed. Chest radiography after thorax drainage also disclosed a pneumopericardium. The 12-lead electrocardiogram recorded before the thoracic drainage revealed an ST-segment elevation, which normalized after the surgical procedure. Ischemic myocardial biomarkers were negative. The authors call attention to the right-sided pneumothorax associated with pneumopericardium as an unusual cause of ST-segment elevation.Keywords: Electrocardiography; Pneumothorax; Pneumopericardium; Asthma; Barotrauma. CASE REPORTA 47-year-old female patient was admitted to the emergency department with a 3-day history of dyspnea, cough, and wheezing. She denied fever and other complaints. She referred a past medical history of asthma and hypertension and was taking an inhaled bronchodilator and a corticosteroid.On physical examination, the patient was alert, oriented, and hydrated. The blood pressure (BP) = 150/80 mmHg, pulse rate = 152 beats per minute, respiratory rate = 32 respiratory movements per minute (rmpm). The patient looked distressed using the accessory muscles of breathing during inspiration, and the room air pulse oximetry was 88%. Lung examination showed diffuse highpitched expiratory wheezes. The initial diagnosis was bronchospasm caused by an asthma attack.She was promptly treated with corticosteroids, magnesium sulphate, and inhaled bronchodilators. Non-invasive ventilation was attempted with continuous positive airway pressure of 10 cm H2O, followed by orotracheal intubation and mechanical ventilatory support.
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