Aims To evaluate the quality of life (QoL) and burden of primary caregivers of children and young adults (PCCYAs) with and without disabilities. Methods A cross‐sectional study was carried out with sample composed of 336 PCCYAs with cerebral palsy (CP; n = 84), Down syndrome (DS; n = 84), autism spectrum disorder (ASD; n = 84), and without disabilities (control group: CG n = 84), matched by gender and age. The burden of caregivers was assessed with the Zarit Burden Interview (ZBI), whereas QoL was assessed using the WHOQOL‐BREF instrument. Results QoL and burden of CG presented better results compared to groups with disabilities, with the lowest environmental domain of all study groups (P <.001). The prevalence of burden was moderate for PCCAs of groups with disabilities. There was association between all WHOQOL‐BREF and ZBI domains and variables age, schooling, occupation and per capita income (Spearman's correlation coefficient, P <.05). There is a negative impact on WHOQOL‐BREF, with an increase in the level of burden of PCCAs with disabilities. Conclusion The majority of PCCYAs were unemployed married mothers, with low schooling and health problems. Older caregivers experience even higher burden and greater impact on QoL.

Abstract

The use of star anise oil from a natural source as a dienophile in the multicomponent double Povarov reaction (MCPRs) to produce highly substituted julolidines with diverse technological applications is described. Within the framework of green chemistry, these MCPRs have many advantages such as (i) use of water in the reaction, (ii) creation of up to six bonds in one sequence, (iii) water as a sole waste, (iv) 100% of carbon economy, (v) a metal-free process, and (vi) nontoxic and reusable organocatalysts. These advantages, along with a simple workup procedure, make this protocol greener for the synthesis of julolidines.

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A depressão é um transtorno de humor de prevalência crescente, capaz de reduzir a produtividade profissional do indivíduo em 10% e considerada uma das doenças mais incapacitantes. No Brasil, atinge 11,5 milhões de pessoas e é uma das maiores causas de afastamento do trabalho. Uma das profissões vulneráveis é o magistério, que lida com baixa remuneração, falta de recursos materiais e estrutura, alta carga horária, excesso de cobrança, entre outras questões. O objetivo do estudo foi analisar o perfil dos docentes da rede pública que se afastaram por depressão, entre 2009 e 2017, bem como avaliar as características do afastamento e o índice de reincidência. A coleta foi realizada através do banco de dados informatizado da perícia médica da Secretaria de Estado do Planejamento, Orçamento e Gestão de Sergipe e incluiu 239 docentes. Esses profissionais eram predominantemente do sexo feminino, com ensino superior completo, casados e de meia-idade. A depressão foi a principal causa de afastamento do trabalho, quando comparada aos demais transtornos mentais. A carga horária cumprida foi de 200 horas mensais, com tempo médio de serviço de 18,5 anos e média de 194,5 dias de afastamento, sendo o código F32 da Classificação Estatística Internacional de Doenças e Problemas Relacionados à Saúde, 10ª edição (CID-10), o mais prevalente. Mais da metade dos profissionais apresentou reincidência, perfazendo média de 4,04 recidivas por docente. Trata-se de uma pesquisa singular, a respeito de uma realidade pouco estudada no cenário nacional e nunca estudada em Sergipe, que impõe a necessidade de investigação imediata, de forma a facilitar o planejamento e a implementação de melhorias.