Infectious disease specialists are frequently consulted for diagnostic and therapeutic advice on challenging cases. When evaluating patients, the infectious disease specialist is well positioned to offer an appropriate diagnostic approach but is also at risk of not recognizing the correct diagnosis for a variety of reasons. We believe it is important to provide infectious disease specialists and trainees with a fundamental understanding of diagnostic errors, clinical reasoning, and cognitive biases. We present 2 cases demonstrating common cognitive biases leading to diagnostic errors, and we reflect on strategies that may aid in their prevention. We hope to provide knowledge and tools that may help prevent diagnostic errors in the future.

Ocular complications in cryptococcal meningitis (CM) are commonly attributed to elevated intracranial pressure (ICP). We report a case of reversible vision loss complicating AIDS-related CM with a normal ICP. We review other cases of blindness in CM with normal ICP and the potential role of corticosteroids as treatment.

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Focusing on disenchantment, sociology undertheorizes wonder. Our analysis of 30 interviews is the first sociological study of Americans’ wonder experiences. Contrary to Weber’s theorization of disenchantment, this study shows people experience wonder that is transformative and try to cultivate states of mind open to wonder experiences. Our study shows wonder follows from particularity, difference, and encounters with the mysterious; wonder connects people to expansive concerns; people experience acute self‐awareness during wonder encounters; and people seek wonder experiences. Wonder communities influence wonder experiences, but stages of wonder experiences are similar outside communities.