Background: Preceptor ship is a clinical teaching model through which undergraduate nursing students are facilitated to acquire beginning competencies that enable them to function effectively in the complex workplace environment upon graduation. The aims of the current study were to evaluate the effect of tailored educational program about selected clinical measurements regard learning process on nursing preceptors (knowledge) and evaluate the preceptor abilities by their perceptee before the educational program. Quasi-experimental (pre-posttest) research design was used. The study was conducted at Faculty of Nursing and Institute of Nursing which affiliated to Minia University and Institute of Nursing which affiliated to Beni Suef University. Purposive study sample included Sixty one (61) preceptors recruited from previous mentioned settings as following: Group I (n=31) & Group II (n=30) respectively, Two tools was utilized, the first one was a structured self-administered questionnaire: to collect personal data of the preceptor and their knowledge regarding selected clinical measurements, the second one: were used to evaluate the preceptor"s abilities which collected from the preceptees before the educational program. Results: revealed that Mean ±SD age regarding study participant (group1) equal 28.1+-4.7, about three quarter of participant (74.2%) have baccalaureate of nursing , the Mean ±SD related to the years of experiences was 6.7+-4.9. The majority of them (96.8%) hadn't receiving any staff developmental training program. Lastly the study cleared that total participant (100%) haven"t ongoing any educational program. There are a highly statically significant differences in knowledge between pre and posttest regarding selected clinical measurements that improving nursing preceptor's role among both studied groups p-value= .001**. Conclusion there are improvement in knowledge about selected clinical measurements that improving nursing preceptor's role among both studied groups and the precepts evaluation regarding highest abilities for their preceptor were according to they mentioned as their preceptor available when need help, provide feedback about program, actively sought educational opportunities….ect. Recommendation: the recent study recommended that it is important to design a Preceptorship programs or academy that develop a courses as the best starting point to increase the effectiveness preceptor role and which will reflect on the development of specific skills in their perceptee students