Background: The aim of the study was to determine the various types of congenital or acquired disorders causing permanent disability and their association with age, sex and visual acuity in patients attending disability clinic of department of ophthalmology, Jorhat medical college and hospital, Assam, from January 2018 to December 2018.Methods: A hospital-based cross-sectional study. 200 patients were enrolled in the duration of January 2018 to December 2018 and were analyzed for anomalies, etiology, sex and age at presentation.Results: Out of 200 cases analysed, 116 males and 84 females (Male: Female = 1.38:1) observed. The most common age group at presentation was 11-20 years (28.5%). 23% of cases were congenital. The most frequent ocular anomaly noted was microphthalmos (19%) followed by uveal coloboma (15%) and phthisis bulbi (14%).Conclusions: In a developing country like India, a large proportion of the childhood and adult blindness is avoidable. Action is needed to prevent blindness from vitamin A deficiency, measles, external ocular infections and chemical injuries. Specialist paediatric and optical services are required to manage cataract and glaucoma. Further work is indicated to elucidate the causes of anophthalmos, microphthalmos and coloboma. It would be useful to document the changing patterns in the causes of ocular disability to allow early action against emerging avoidable causes.

Background: To screen for ocular finding of optic nerve involvement in patients with tuberculosis and documents these findings.Methods: The hospital based observational study was carried out in a tertiary care hospital in Assam  for  the duration of July 2018 to June 2019 in 384 diagnosed cases of tuberculosis patients who fulfil  the inclusion criteria during the study period.Results: 11 cases with optic nerve involvement was found out of 384 tuberculosis patients. Most common presenting complain was blurring of vision. Unilateral involvement was maximum. Most common finding was disc oedema.  Ocular TB cases was higher in extrapulmonary TB patients.Conclusions: Diagnosis of ocular Tb is mainly presumptive, based on history, clinical examination, adjunctive diagnostic tests and response to anti tuberculous therapy. Amongst 384 TB cases ocular manifestations were found in 11 cases and therefore, we can conclude that ocular manifestations hold significance in extra pulmonary manifestations of TB. So, TB patients need to have routine ocular examination for the early diagnosis and timely management.