Background: The diagnostic test for malaria is mostly based on Rapid Diagnostic Test (RDT) and detection by microscopy. Polymerase Chain Reaction (PCR) is also a sensitive detection method that can be considered as a diagnostic tool. The outcome of malaria microscopy detection depends on the examiner's ability and experience. Some RDT has been distributed in Indonesia, which needs to be evaluated for their results. Objective: This study aimed to compare the performance of RightSign RDT and ScreenPlus RDT for detection of Plasmodium in human blood. We used specific real-time polymerase chain reaction abTESTMMalaria qPCRII) and gold standard of microscopy detection method to measure diagnostic efficiency. Methods: Blood specimens were evaluated using RightSign RDT, ScreenPlus RDT, Microscopy detection, and RT-PCR as the protocol described. The differences on specificity (Sp), sensitivity (Sn), positive predictive value (PPV), and negative predictive value (NPV) were analyzed using McNemar and Kruskal Wallis analysis. Results: A total of 105 subjects were recruited. Based on microscopy test, RightSign RDT had sensitivity, Specificity, PPV, NPV, 100%, 98%, 98.2%, 100%, respectively. ScreenPlus showed 100% sensitivity, 98% specificity, 98.2% PPV, 100% NPV. The sensitivity of both RDTs became lower (75%) and the specificity higher (100 %) when using real-time PCR. Both RDTs showed a 100% agreement. RT-PCR detected higher mix infection when compared to microscopy and RDTs. Conclusion: RightSign and ScreenPlus RDT have excellent performance when using microscopy detection as a gold standard. Real-time PCR method can be considered as a confirmation tool for malaria diagnosis.

Atherogenic Index of Plasma (AIP) as a new marker of atherogenicity and directly related to the risk of atherosclerosis, is a simpleand inexpensive method to assess the severity of atherogenic dyslipidemia. 97% of adult patients with type 2 DM (T2DM) will havedyslipidemia including increased levels of TG, low HDL-C levels whereas LDL cholesterol levels had no effect. To determine the atherogenicindex of plasma in controlled and uncontrolled T2DM. A Cross-sectional study was conducted on 72 controlled T2DM samples and 112uncontrolled T2DM samples from Clinic of Endocrine and Methabolic dr Wahidin Sudirohusodo Hospital Makassar, starting from April-May 2013. Fasting glucose level, triglycerides, HDL-C and HbA1c determined using ABX Pentra 400 (colorimetric method). Data thenanalyzed with Mann Withney U test. Most of the samples are male, with the age range from 51-60 years old. Mean AIP is not so differentbetween the two groups (0.51±0.28 and 0.55±0.28 respectively). Fasting glucose level, triglycerides, HDL-C in T2DM uncontrolled werehigher than controlled. The atherogenic index of plasma of controlled T2DM group were 0.93 times lower than uncontrolled T2DM, MannWithney U test showed that there were no significant correlation between both of group (p>0.05). Atherogenic index of plasma cannotbe used to distinguish between controlled and uncontrolled T2DM.