Objective: To determine the association of quantitative ST– segment depression with early mortality within 30 day in patients with first non-ST – segment elevation acute coronary syndrome (NSTE-ACS). Methodology: This descriptive case series study was conducted at the cardiology department of LUMHS, from October 2016 to March 2017. Patients with NSTE-ACS and positive cardiac biomarkers, patients older than 25 years and both genders admitted to CCU were included. The ST-Segment depression was assessed on 12 lead electrocardiography. The ST segment is the line that starts from the end of the QRS complex (J wave) to the beginning of the T wave. Normally ST segment is straight line and, isoelectric to base line, ST segment depressed below isoelectric line is said ST depression, down sloping or flat depressed ST segments indicate coronary ischemia, more than 0.5 mm ST depression significant for ischemia. All patients were followed for 30-days for early mortality. All information obtained was recorded on the study Performa. Results: A total of 148 cases with acute myocardial infarction were integrated; the patient's average age was achieved as, 42.5±5.43 years, and males were in the majority 96(64%). On electrocardiography, ST-Segment depression was found in 60.13%, which is further divided into 0.5mm, >0.5-0.9 mm, >1-1.9 mm, and >2 mm with percentages of 12.83%, 22.29%, 16.89%, and 8.12%, respectively. Short term mortality was significantly associated with the severity of ST segment depression score (p-value 0.001). Conclusions: In the study conclusion, the severity of ST-Segment depression score was observed to be significantly correlated with short term mortality (30-day) in cases with early NSTE-ACS.

Objectives: To evaluate the association of echocardiographic wall motion score (WMS) with early mortality (30-days) among patients with non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS). Material and methods: This descriptive case series study was conducted at the cardiology department at LUMHS from October 2015 to March 2016. Patients with NSTE-ACS and positive cardiac biomarkers, patients older than 25 years, and both genders admitted to CCU were included. Standard indoor treatment was done in these patients. Evaluation of wall motion score was done by echocardiography by 2D echo. All patients were monitored for early cardiac event-related mortality (30 days). The self-made Performa logged all of the information gathered. SPSS version 26.0 was used to analyze all of the data. Results: In this study, a total of 148 cases of NSTE-ACS were studied. Most of the patients were aged more than 40 years, and males were in the majority 93(62.8%). Reginal wall motion was in 105(70.9%) of the cases. In 88(59.5%) of the cases, the ejection fraction was <40% and in 58(40.5%) of the cases it was >40%. CKMB was raised in 69(46.6%) of the cases, and troponin T was positive in all of the cases. The overall short-term mortality rate was 20.3%, which was significantly associated with a high grade of wall motion score (p-0.001). Conclusions: It was concluded that echocardiographic wall motion score was correlated significantly to short-term mortality (30-day) among new patients presented with NSTE-ACS. Keywords: Acute coronary syndrome, WMS, NSTE, early mortality