Non-invasive estimation of intracranial pressure by diffuse optics -a proof-of-concept study Running title (40/45 characters): Non-invasive estimation of ICP by optics Table of contents title (75/75 characters): Non-invasive estimation of ICP by diffuse optics -a proof-of-concept study

We present a proof-of-principle of a method for non-invasive estimation of intracranial pressure in infants and adults based on the pulsatile cerebral blood flow measured by diffuse correlation spectroscopy and employing a recurrent neural network.

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A wearable, low-cost device was developed for measuring cerebral blood flow using speckle contrast optical spectroscopy. We present its design and results from different protocols during realistic scenarios taking advantage of it being a wearable device.

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