Low back pain is an increasingly prevalent and costly issue in the United States. It is a particularly relevant problem for Workers' Compensation patients, who typically experience worse surgical and functional outcomes than their non-compensated counterparts. Neuropsychologists often provide intervention and assessment services to compensated patients with back pain, and thus it is critical they possess a basic understanding of the factors that might predispose an injured worker to poor spine surgery outcomes. This paper will review the current literature regarding presurgical biopsychosocial factors which have been implicated in poor back surgery outcomes among injured workers. We provide some tentative guidelines for neuropsychologists to utilize in providing services to injured workers with back pain.