No abstract

Background: Perinatal depression has been linked with deleterious child development outcomes, yet

Appendix A: Baseline characteristics of women who do versus do not have 6-month post-childbirth outcome data for the primary endpoint analysis. Have 6-month outcome data for the primary endpoint analysis No (n=117) [1] Yes (n=453) p-value [2] Age, years (mean (SD)) 27 (5.1) 27 (4.7) 0.54 Marital status (n (%)) Married 117 (100%) 453 (100%) -Occupation (n (%)) Does not work Manual worker Non-manual worker 109 (93%) 6 (5%) 2 (2%) 424 (94%) 25 (6%) 4 (1%) 0.77 Education status (n (%)

No abstract

Background: The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and energy homeostasis. PTP1B is encoded by the PTPN1 gene located on chromosome 20q13 showing linkage with type 2 diabetes (T2D) in several populations. PTPN1 gene variants have been inconsistently associated with T2D, and the aim of our study was to investigate the effect of PTPN1 genetic variations on the risk of T2D, obesity and on the variability of metabolic phenotypes in the French population.