One of the co-authors of this article has changed her name due to her personal reason. Fateme Sasannia should be changed to Sarvin Sasannia.Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Corona virus disease 2019 (COVID-19) is a contagious viral respiratory disease that is still a major global cause of mortality. The disease is characterized by common signs and symptoms such as fever, fatigue, dry cough, and shortness of breath, and it can also cause acute respiratory distress syndrome (ARDS) in severe cases. 1 As a matter of fact utilization of corticosteroids in COVID-19 hospitalized patients to modulate inflammation-mediated lung injury and lower mortality rates may expose patients to opportunistic bacterial and fungal infections which in turn may lead to death. 2 Currently, mucormycosis, an invasive fungal infection associated with COVID-19 infection, can cause widespread dissemination during treatment or after hospital discharge. Mucormycosis is a rare, angioinvasive fungal infection that rapidly progresses with significant morbidity and mortality. 3 Cutaneous mucormycosis due to angioinvasion has the potential for rapid death if treatment is not proper and quick. 4,5 Previous studies and literature have shown that mucormycosis is a highly aggressive disease, highlighting the necessity of early diagnosis and treatment initiation. Systemic antifungal medication, primarily intravenous amphotericin B (AMB), and vigorous surgical debridement, are the cornerstones of mucormycosis treatment. 4,6
Backgrounds: Infection is one of the major threats to liver transplant patients and significantly affects associated mortality and morbidity. Serious infections are likely to occur a few months after transplantation, and most of them are bacterial. The aim of this study was to evaluate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in liver transplant patients. Materials & Methods: In this systematic review and meta-analysis, Preferred Reporting Items for systematic reviews and meta-analysis guidelines were used. International databases including PubMed, Scopus, Web of Sciences, Embase, and Cochrane were searched by related MeSH terms and keywords for studies published until July 26, 2020. The current study was registered by a pre-defined protocol in PROSPRO. Findings: After a comprehensive literature search, 11 articles were selected for inclusion in the analysis. The prevalence of MRSA in liver transplant patients was 75% (95% CI: 58% -89%); however, an evident heterogeneity was observed between the studies (I 2 = 87.84%, p< .001).
Conclusion:In conclusion, this study results demonstrate that the prevalence of posttransplant MRSA colonization bacteremia is high among liver transplant patients. This should be considered seriously, and efforts should be made to prevent mortality in this group of patients.
The link and association between COVID‐19 and Alzheimer's disease (AD) is controversial. This study aims to investigate whether COVID‐19 was associated with a different presenting clinical picture or a more severe course of illness (eg intubation and death) in people with AD in this study cohort.
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