No abstract

No abstract

Grafting of material with organic functionalities helps to tune material's surface properties. Surface properties of a biomaterial play a significant role for sustained release of therapeutic agent. To evaluate the effect of tartaric acid concentration on HA surface properties and phase purity, a series of tartaric acid grafted HA (t-HA) samples were prepared via in situ wet chemical synthesis. Grafting of HA with tartaric acid improved its surface properties. The surface area of 737 m 2 /g was gained when 0.05 mole equivalent of tartaric acid was used for HA grafting. X-ray diffraction patterns of t-HA samples have shown low degree of crystallinity compared to HA sample. XRD results showed the formation of calcium tartrate phase along with HA when higher concentration of tartaric acid was used for synthesis. The HA and t-HA samples were explored for the delivery of moxifloxacin. High surface area, surface charge and low degree of crystallinity have improved electrostatic interaction between the drug and t2-HA and help in sustained release of moxifloxacin. In vitro antibacterial activity of drug loaded samples showed activity against S. aureus. Calcium tartrate containing samples t3-HA, t4-HA and t5-HA showed, however, moderate inhibition against S. aureus without drug. In vitro cell studies by using MC3T3 cell line showed that prepared HA and t-HA samples did not exhibit any cytotoxic effect.

In a WLAN-cellular integrated network scenario, the most important point of consideration is the vertical handoff strategy applied for WLAN admission control. The admission control has previously been based on the parameters like congestion level in WLAN network. We propose a novel approach for handoff to WLAN by using connectivity graph data from online social networking services. Stronger social ties with other users advocate a higher probability of admission to WLAN. The main benefit of proposed handover strategy is diminution in global social network traffic. Simulation results prove the validity of our proposed approach against conventional methods.

Medicinal plants produce natural chemicals either pure or in the form of mixture of compounds which are diverse in nature. These compounds show activities which are very important for human health such as antioxidant activity, antimicrobial effect, anti-helminths activity, anti-inflammation activity, immune system activation, decrease of platelet aggregation, treatment of diabetes and modulation of hormone metabolism and anticancer property.  Demand of these natural compounds is increasing therefore it is needed to develop the more effective methods for extraction of these compounds. Foeniculum vulgare Mill. is one of the most commonly used medicinal plants used in cure of many diseases. In present study the experimental design was developed for the extraction of compounds specially “L-fenchone”, an essential part of fennel essential oils by Microwave Assisted Extraction (MAE) from seeds of F. vulgare. Extraction was done in hexane from different particle sizes (40μ and 80μ) of plant material at 600W of microwaves power in 1 and 5 mint. Gas chromatography mass spectroscopy (GCMS) was used for the quantification of L-fenchone. MAE was proved to be an efficient and rapid method of extraction from seeds of F. vulgare. Highest amount was extracted from 80μ, which was 183.33 mg per gram of plant sample. MAE consumed lesser energy by taking lesser time (5 minutes) for extraction. It proved to be cost effective technique as consumed lesser solvents and samples.