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Natural catastrophes like earthquakes have the potential to be fatal by claiming lives and harming infrastructure, the environment, and mental health. Victims may experience symptoms such as anxiety, despondency, and post‐traumatic stress disorder. Recent earthquakes in Turkey and Syria caused enormous destruction and a high number of fatalities, which is growing by the day. The past examples of earthquakes in China, South Asia, and Turkey imply that there is a possibility that the victims may feel isolated and under psychological stress. Our article outlines the high strategies to minimise the risk of mental health problems among victims of Turkey and Syria.

Recently, Ruxolitinib (Opzelura) has been approved by the Food and Drug Administration (FDA) as the first treatment for non-segmental vitiligo, which results in chalky white macules with clear edges due to an autoimmune disorder. The mode of action of this cream is JAK inhibition which progressively enhances the growth of new, healthy skin cells, and eventually, repigmentation occurs in the affected area. Indeed, this medication represents significance in the field of dermatology as almost 3/4th % of facial vitiligo was resolved but the high cost will be a hindrance in facilitating the patients and should be subsidized. Moreover, prescribers and pharmacists should be aware of the black box warnings issued by FDA as severe caution is indicated. More clinical trials should be conducted to know the safety of children under 12 years of age. Highlights

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Pakistan's 200 million people are among the most vulnerable global victims of the escalating effects of climate change despite producing <1% of the greenhouse gases blamed for contributing to global warming. Flooding is one of its consequences. 1Since the monsoon season started, Pakistan has received more than 60% of the usual rainfall. In Baluchistan, Khyber Pakhtunkhwa, and Sindh, flooding, landslides, flash floods, and severe weather-related calamities like glacial lake outburst floods have drastically affected the areas. 2 One-third of the country has been swamped by the disaster, which has afflicted at least 33 million people. This has exposed 3.4 million children to waterborne infections, drowning, and malnutrition. 2-4 Rains and floods have destroyed about 300,000 homes and damaged over 650,000 more. Livelihoods have been shattered as crops have been destroyed, 2 million acres of agricultural land have been damaged, and approximately 735,000 cattle have died. 4 In flood-affected communities, the latest floods have also exacerbated food insecurity and hunger situation. From December through March 2023, over 14.6 million people are anticipated to need emergency food assistance. 5All the data stated above has raised various concerns related to nation's socioeconomic and demographic situation, this catastrophic flooding has elevated the dangers of dealing with the already burdened and compromised