Global increase in the level of antimicrobial resistance among bacterial pathogens has prompted the search for alternative treatment from medicinal plants. Phyllantus muellerianus leaves has been used traditionally against microorganisms of medical importance, hence the need to evaluate the pharmacological pathways and mode of actions using in vitro and in silico approaches. Clinical isolates of eight ( 8) microorganisms associated with urinary tract infections were obtained and identified using morphological and biochemical methods. Phyllantus muellerianus leaves were extracted and purified by solvent partitioning. Ethyl acetate fraction of PM had the highest yield and zone diameter range from 13.5 ± 1.00 to 28 ± 1.53 mm. The rate of protein leakage per time interval of Staphylococcus aureus increased from 9.29 μg/ml at 0 min to 17.43 μg/ml at 120 min while leakage in Candida albicans also increased from 8.57 μg/ml at 0 min to 70.43 μg/ml at 120 min. GCMS fingerprints, pharmacodynamics and pharmacokinetic studies revealed the active agent as quindoline, an azaindole and isotere of indoles having a binding energy of −9.1 kcal/mol. Analyses of the structural and atomic orientations of quindoline, and superimposition on ciprofloxacin, a common antibiotic revealed an interesting comparison, effecting a stronger binding affinity of Quindoline-HMG-CoA complex.

Emerging contaminants have posed major environmental and health challenges to human and aquatic lives. They include pharmaceuticals, endocrine disrupting compounds (EDCs), persistent environmental pollutants and many more. EE2 is an example of an endocrine disrupting compounds (EDCs) increasingly gaining acceptance and used to augment the deficiencies of other reproductive hormones. EE2 constitutes environmental nuisance via discharge into aquatic bodies, thus, threatening aquatic lives and resulting in health defects in human. It is worthy of note that previous researchers have channeled their studies to identifying ways of expelling EE2 from the environment. However, they remain persistent in the environment. The current review examined biological, chemical, physical and nanotechnological approaches in expelling EE2 from the environment. All methods discussed have been efficient in EE2 removal. From the review, both independent and combinatorial approaches in EE2 removal has yielded efficient results.

Camel milk and urine consumption is an age-long tradition amongst the Arabs for 14 centuries. Camel urine and milk consumers had attested to its miraculous healing properties most especially against terminal illnesses. Although, camel urine and milk consumption is challenged by non-acceptance by World Health Organization and other related health authorities; some individuals still find healing in its consumption. This study takes a look at consumers’ perception of camel urine and milk consumption and its related medical significance. Four countries (Nigeria, Somalia, Turkey and Pakistan) were the research areas used in the survey. The research involved 1000 respondents. From the survey, participants from Nigeria were more than half (62%) of the total participants. More than 80% of the participants believed in the healing power of traditional medicine. Camel milk and camel urine were consumed for health-related issues by 48.4% and 40.1% of participants respectively. More than half (57.5% and 70.4%) of the participants claimed that consumption of camel milk and camel urine is not authorized in their respective countries. The study showed that camel urine and milk consumption is evident in our survey area. We, therefore, implore health regulatory authorities in these countries to fund camel research.

Covid-19 pandemic is a global health issue that adversely affected every sector of the world’s economy. Fruits are known to be a source of vitamins providing the body with necessary defense against infections (inclusive of Coronaviruses). Nigerians prefer to buy ready-to-eat (RTE) fruits than whole fruits due to their high prices. Consumer perception of RTE fruits sold in Ogun and Lagos, Nigeria during the Covid-19 pandemic months in 2020 and within January and March 2021 via an online survey were compared. Ogun and Lagos states were selected because they represent major entry routes for land and air travel into Nigeria respectively. 500 respondents were obtained with 49.7% each as male and female respectively in Ogun state while Lagos had 49.5% and 50.5% of the male and female gender. In addition, the predominant age group that responded to the questionnaire falls within 21 – 30 with 49.7% in Ogun state and 54.1% in Lagos state. 96.1% of the respondents in Ogun state had a tertiary education while 99% was recorded to possess tertiary education in Lagos state. 34% respondents took RTE fruits 2- 3 times a week, 31.2% less than once a week while only 2.8% took RTE fruits 4 – 5 times a week. From the survey, 84% of the respondents were aware that fruits possess needed vitamins to fight infections while only 87.4% of the respondent were aware of fruit borne poisoning and have knowledge of fruit borne pathogens like Staphylococcus aureus, Escherichia coli, Klebsiellaspp, Pseudomonas aeruginosa, Penicilliumspp, Aspergillusnigerand Rhizopusstolonifer. This study shows that fruit consumers neglected health consciousness in the purchase of RTE fruits in Ogun and Lagos in the first 3 months of 2021 compared to 2020. This negligence may result in a spike of another Covid-19 wave in Ogun and Lagos if the necessary food and health regulatory authorities fail to act timely. Also, the application of an effective hazard analysis and critical control point (HACCP) application reduces the chance of contamination of ready- to- eat fruits.