Childhood cancer is a priority in Egypt due to large numbers of children with cancer, suboptimal care and insufficient resources. It is difficult to evaluate progress in survival because of paucity of data in National Cancer Registry. In this study, we studied survival rates and trends in survival of the largest available cohort of children with cancer (n = 15 779, aged 0‐18 years) from Egypt between 2007 and 2017, treated at Children's Cancer Hospital Egypt‐(CCHE), representing 40% to 50% of all childhood cancers across Egypt. We estimated 5‐year overall survival (OS) for 14 808 eligible patients using Kaplan‐Meier method, and determined survival trends using Cox regression by single year of diagnosis and by diagnosis periods. We compared age‐standardized rates to international benchmarks in England and the United States, identified cancers with inferior survival and provided recommendations for improvement. Five‐year OS was 72.1% (95% CI 71.3‐72.9) for all cancers combined, and survival trends increased significantly by single year of diagnosis (P < .001) and by calendar periods from 69.6% to 74.2% (P < .0001) between 2007‐2012 and 2013‐2017. Survival trends improved significantly for leukemias, lymphomas, CNS tumors, neuroblastoma, hepatoblastoma and Ewing Sarcoma. Survival was significantly lower by 9% and 11.2% (P < .001) than England and the United States, respectively. Significantly inferior survival was observed for the majority of cancers. Although survival trends are improving for childhood cancers in Egypt/CCHE, survival is still inferior in high‐income countries. We provide evidence‐based recommendations to improve survival in Egypt by reflecting on current obstacles in care, with further implications on practice and policy.
One of the mummifid foetuses fiom the tomb of Tutankhamun displays what must be the earliest evidence of Sprengel's deformity. The f m l e foetus is still-born, aged eight months or, at the most, nine months. There is radiographic evidence of dislocation at C5/6, tibia vara and increased metaphysial density. Serological investigation of tissue fiom the foetus suggests the presence of bloodgroup M and H substances. Possible rehtionships of this foetus to other pharaonic remains already
the jirst public account to appear in print of the $indings of their re-investigation in 1968 of the mummy of Tutankhamun. Our readers will be as fascinated as we have been at this demonstration of the possibility of determining human relationships between people living over three thousand years ago. This should be read in conjunction with the article by Professor Fairman which follows this (pp. 15-18).
SUMMARY
The ascorbic acid content of a total of 120 specimens of each species of edible liver was estimated by the N‐bromosuccinimide method. Statistical analysis of the results is given. Differences were found occasionally between males and females in liver ascorbic acid content, but were not statistically significant. The effect of cooking on liver ascorbic acid content is shown.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.