Background Cerebrovascular diseases are considered a very hard burden as they may lead to poor outcome, and they are considered the second most common cause of morbidity and mortality after coronary artery disease. They include wide variety of diseases that affect vascularity of brain tissue with the most common one is stroke—either ischemic or hemorrhagic. The aim of the current study was to assess the role of susceptibility weighted imaging (SWI) in imaging of different cerebrovascular diseases and what would be added by SWI to different routine magnetic resonance imaging (MRI) sequences. Results Fifty-five patients enrolled in this study, 14 patients had lesions with calcifications, 13 patients had cavernoma, 10 patients had diffuse axonal injury, 11 patients with infarction, 2 patients with AVM, 2 patients with chronic microbleed, 2 patients with hemorrhage, and 1 patient with hemorrhagic tumor, and the result showed that SWI has sensitivity 100%, specificity 60%, and accuracy 91.9% in regard to diagnosis of cavernoma while sensitivity 91.7%, specificity 50%, and accuracy 85.7% in regard to diagnosis of calcification and regarding diagnosis of diffuse axonal injury; SWI has 98.3% sensitivity, 100% specificity, and 98.4% accuracy; finally, in regard to diagnosis of hemorrhagic lesions, SWI has 96.1% sensitivity, 66.7% specificity, and 93.1% accuracy. Conclusion SWI is very sensitive in the diagnosis and detection of actual number of vascular malformation like cavernomas than conventional MRI. SWI adds significant diagnostic value to routine MRI sequences in regard to calcification that was nearly limited in its diagnosis by CT. Diagnosis of microbleeds becomes easier and accurate with SWI. Diffuse axonal injury was and still considered a clinical diagnosis, but SWI becomes the gold standard in its imaging diagnosis confirming the clinical one.