BackgroundIn 2015, the United States Preventive Services Task Force (USPSTF) recommended targeted screening for prediabetes and diabetes (dysglycemia) in adults who are aged 40 to 70 y old and overweight or obese. Given increasing prevalence of dysglycemia at younger ages and lower body weight, particularly among racial/ethnic minorities, we sought to determine whether the current screening criteria may fail to identify some high-risk population subgroups.Methods and FindingsWe investigated the performance of the 2015 USPSTF screening recommendation in detecting dysglycemia among US community health center patients. A retrospective analysis of electronic health record (EHR) data from 50,515 adult primary care patients was conducted. Longitudinal EHR data were collected in six health centers in the Midwest and Southwest. Patients with a first office visit between 2008 and 2010 were identified and followed for up to 3 y through 2013. We excluded patients who had dysglycemia at baseline and those with fewer than two office visits during the follow-up period. The exposure of interest was eligibility for screening according to the 2015 USPSTF criteria. The primary outcome was development of dysglycemia during follow-up, determined by: (1) laboratory results (fasting/2-h postload/random glucose ≥ 100/140/200 mg/dL [5.55/7.77/11.10 mmol/L] or hemoglobin A1C ≥ 5.7% [39 mmol/mol]); (2) diagnosis codes for prediabetes or type 2 diabetes; or (3) antidiabetic medication order. At baseline, 18,846 (37.3%) participants were aged ≥40 y, 33,537 (66.4%) were overweight or obese, and 39,061 (77.3%) were racial/ethnic minorities (34.6% Black, 33.9% Hispanic/Latino, and 8.7% Other). Overall, 29,946 (59.3%) patients had a glycemic test within 3 y of follow-up, and 8,478 of them developed dysglycemia. Only 12,679 (25.1%) patients were eligible for screening according to the 2015 USPSTF criteria, which demonstrated the following sensitivity and specificity (95% CI): 45.0% (43.9%–46.1%) and 71.9% (71.3%–72.5%), respectively. Racial/ethnic minorities were significantly less likely to be eligible for screening yet had higher odds of developing dysglycemia than whites (odds ratio [95% CI]: Blacks 1.24 [1.09–1.40]; Hispanics 1.46 [1.30–1.64]; and Other 1.33 [1.16–1.54]). In addition, the screening criteria had lower sensitivity in all racial/ethnic minority groups compared to whites. Limitations of this study include the ascertainment of dysglycemia only among patients with available test results and findings that may not be generalizable at the population level.ConclusionsTargeted diabetes screening based on new USPSTF criteria may detect approximately half of adult community health center patients with undiagnosed dysglycemia and proportionately fewer racial/ethnic minorities than whites. Future research is needed to estimate the performance of these screening criteria in population-based samples.
Sand production can be challenging for many operators in unconsolidated formations. The production of formation sand and fines can cause erosion damage to both surface and downhole equipment, resulting in major well intervention and sand disposal costs. Conventional resin consolidation systems have been successfully used to prevent solids production in short, homogenous intervals. However, resin consolidation attempts in longer intervals have resulted in erratic success rates, which could be attributed to a lack of complete and uniform treatment of the entire interval length. A recently developed aqueous-based resin (ABR) system has helped provide effective and efficient treatment of significantly longer intervals, has improved health, safety, security, environmental (HSSE) compatibility, and can help improve various operational considerations. This paper discusses results of laboratory testing and the subsequent successful treatment using the ABR system within a well located in Nile Delta, which was the first attempt of its kind in Egypt. Sieve analysis revealed unsorted formation sand, which usually requires a gravel pack completion, rather than a standalone screen; however, because of limitations with respect to wellbore diameter (5 in.), it was difficult to complete the well using conventional gravel pack completion methods. Additionally, the well had a history of unsuccessful treatment using a non-resin product, which modifies the surface potential charges of the sand grains and reduces the repelling forces between them. The well was still producing sand after that treatment; thus, the decision was made to treat the interval using the ABR system. Thereafter, hydrocarbon production, at a rate of 5.5 MMscf/D, was monitored and sand production from the well decreased by more than 95%, with no impairment to hydrocarbon production.
The research aims to present a social reading to recognize the sports satellites’ effect in provoking sports spectators prejudice, the researcher used the descriptive method surveys, and the research community included analyzing two programs of two sports satellites channels, namely: Nile Sport and Modern Sport, both are transmitted on Nile sat and not encrypted. The sample was selected randomly of 1040 spectators: 760 males and 280 females of sports fans watching football on Nile Sport and Modern Sport. In achieving the aim of the research, a tool was prepared and used by the researcher, namely: a football prejudice and sport satellite channels scale, the present research adopted data analysis by SPSS statistical program using and built football prejudice and sport satellite channels scale, that consisted of 23 items divided into two factors: Group I(football prejudice - 13 items)-Group II (the content of satellite sports channels provoking football prejudice -10 items). The most important results came in as follows:(a) Percentage of football prejudice in Group I (sport prejudice) 74.9% among males, while it was 73.7% among females - 76.4% according to the residence of the countryside, while it was 72.3% according to the residence of the countries. And according to the educational level they were as follows: without 71.1%, average 72.8%- above the average 73.8% - university 72.4%. (b) Percentage of football prejudice in Group II(the content of Satellite Sports channels provoking football prejudice) 62.5% among males, while it was 78.1% among females -62.8% according to the residence of the countryside, while it was 76.8% according to the residence of the countries and according to the educational level they were as follows: 66.3% without - 68.5% average - 69.0% above the average - 72.5% university. The researcher recommended using a scale of football prejudice and sports satellite channels; as well as paying attention to the content of satellite sports programs; so as to contribute to reducing the provoking of football prejudice of football public spectators.
Electronic health records represent a rich and growing source of clinical data for research. Privacy, regulatory, and institutional concerns limit the speed and ease of data sharing in this context. We introduce VaultDB, a framework for securely computing SQL queries over the union of private data from two or more sources. VaultDB evaluates queries using secure multiparty computation: cryptographic protocols that securely evaluate a function such that the only information revealed from running them is the query answer. We describe the development of a HIPAA-compliant version of this framework on the Chicago Area Patient Centered Outcomes Research Network (CAPriCORN), a multi-institutional clinical research network that spans the electronic health records of nearly 13M patients over hundreds of clinics and hospitals in the Chicago metropolitan area. Our results from deploying this technology at three health systems within this network demonstrate its efficiency and scalability to conduct multiparty clinical research analyses without moving patient records from their site of origin.
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