No abstract

Cervical cancer is a malignancy of the cervix that can be prevented, but the cause of death of women due to cancer. Cervical cancer is the second most frequent cancer in women in the world. Indirect female sex workers have a higher risk of cervical cancer. The aim of this research was to figure out description of cervical smear examination in indirect female sex workers at hotspot Maredan Tenayan Raya Pekanbaru. Population of this experiment were all indirect female sex workers at hotspot Maredan Tenayan Raya Pekanbaru and samples were taken with total sampling method. The result showed that there were 44 people consist 4% diagnosed with HSIL, 25% were diagnosed with LSIL, 30% diagnosed with ASCUS and 41% with negative for intraepithelial lesion or malignancy (Bacterial vaginosis, Trichomonas vaginalis, Candidiasis presents).

No abstract

The tumor marker CA125 is one of the currently used biomarkers to detect ovarian cancer. The tumor marker CA125 also elevated in other diseases. Human epididymis protein 4 is used as a new biomarker for early detection of ovarian cancer. Human epididymis protein 4 is increased in almost all patients with ovarian cancer and increased only slightly at a fraction of other diseases. Human epididymis protein 4 has a better effectiveness in detecting ovarian cancer when combined with CA125. From the study of literature found that the combination of HE4 and CA125 had a specificity of 96.3% and 92.9% sensitivity.