In the midst of the ongoing and highly polarized immigration debate, it seems that little attention has been paid to how Latinos view efforts to address the issues of undocumented immigrants residing in the United States and enhanced enforcement efforts along the U.S.-Mexico border. Consequently, questions arise as to the degree of support for or rejection of such measures within the Latino community and among the various segments of that community. Do U.S.-born Latinos, foreignborn naturalized citizens, and undocumented immigrants from various parts of Latin America have similar or divergent views on these issues? It is generally assumed that ethnicity is an important factor in influencing attitudes toward immigrants and immigration policies. Some studies have found that foreign-born Latinos have more positive attitudes toward immigration than native-born Latinos due in part to their shared immigration experience. There are, however, other studies demonstrating that Latino immigrants have often expressed support for more restrictive immigration policies. It may hold true, in fact, that many Latinos have ambiguous and conflicting attitudes about these issues. This article will try to shed some light on Latinos' attitudes regarding specific policy measures by analyzing data from the Pew Hispanic Center National Survey of Latinos, which allows for considerable differentiation among various sectors of the Latino population.
The discriminative properties of phencyclidine (PCP) and their generalization to the effects of ketamine and monohydroxylated PCP metabolites were examined in C57BL/6cr mice utilizing two-lever operant procedures. As previously reported for pigeons and rats, PCP was discriminable in this species at a training dose of 3.0 mg/kg. PCP discriminability generalized to test doses of the drug that did not influence response rates (as low as 1.75 mg/kg) and also to ketamine (10 mg/kg). Both PCP monohydroxylated metabolites were active in mice. PCP partially generalized to the monohydroxylated metabolite, 1-(1-phenylcyclohexyl)4-hydroxy piperidine (PCHP) but not to 1-(1-phenyl-4-hydroxycyclohexyl) piperidine (PPC), which is consistent with previous reports on rats. The generalization of the PCP stimulus to PCHP was not as extensive in mice as previously reported for rats, suggesting that it may be less potent in this species. Although PCP discriminability generalized to PCHP, this generalization required PCHP doses that would produce tissue concentrations much higher than could result from discriminable doses of PCP. Therefore, the PCHP metabolite does not appear to mediate PCP discriminability in C57BL/6cr mice.
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