BackgroundOther spectral Doppler parameters can assess joint impairment caused by psoriatic arthritis and psoriasis1.ObjectivesTo detect and compare Doppler velocimetric indexes changes in 3 groups of patients.MethodsThirty – eight patients were evaluated: 8 in the control group – healthy (52 nail beds); 15 in the psoriasis group (134 nail beds); and 15 in the group with psoriatic arthritis (147 nail beds). ”CASPAR” criteria were used to classify the patients. The ultrasound (US) was performed in all patients using Esaote MyLab 50, with high resolution linear probe with a frequency of 18 mHz, it was positioned longitudinally to the nail bed.ResultsThe psoriasis group of patients included 7 males (46.6%) and 8 females (53.4%); 66.6% were white, 33,4% black.Abstract AB1194 – Table 1Mean and standard deviations of US, clinical and laboratory variables by clinical group:Psoriatic ArthritisPsoriasisControl
RI (Resistance Index)0.58 (0.09)0.59 (0.10)0.60 (0.07)PI (Pulsatility Index)1.05 (0.31)1.06 (0.45)1.12 (0.25)Acceleration (A=m/s2;)0.37 (0.29)0.39 (0.47)0.51 (0.44)Acceleration Time (AT=ms)107.30 (37.10)114.64 (41.14)113.10 (40.10)Angle of Insonation(α= °)18.21 (25.8)14.76 (24.71)27.28 (30.10)Nail bed thickness(T=mm)1.60 (0.78)1.68 (0.50)1.44 (0.40)VHS27.5 (24.9)20.4 (14.9)-PCR0.75 (1.1)0.54 (0.7)-Abstract AB1194 – Table 2Distribution and percentage of individuals according to clinical group and to the PASI, NAPSI variables:Psoriatic Arthritis N(%)Psoriasis N(%)Control N (%)
NAPSINormal (=0)0 (0)08 (100)Mild (<20)4 (28,6)10(71,40Severe (>20)11(68,75 (31,3)0PASIMild (<15)14(51,813(48,20Moderate15–251 (50,0)1 (50,0)0Severe (>25)01 (100,0)0Statistically significant: Mean age and SD of the psoriasis, psoriatic arthritis and control groups, respectively: 57.13±14.3 years; 54.66±10.6 years; 24.87±2.03 years (p<0.05). A statistically significant difference was found in the NAPSI variable among all groups (p<0.05); in the variable PASI, a difference was only found in the control group (p<0.05) (Kruskall-Wallis) (table 2); the A variable between the psoriasis group and control (p<0.001); between the psoriatic arthritis group and control (p=0.001), the variable T between the psoriasis and psoriatic arthritis groups (p=0.006) and between the psoriasis and control groups (p=0.001) and the α variable between control and psoriasis groups (p=0.017) (table 1). Spearman and Pearson correlations between US variables per group, psoriasis, psoriatic arthritis and control were: RIxPI r=0.744 (p<0.001), PD (power Doppler)xT r=0.301 (p<0.001), RIxPI r=0.914 (p<0.001), PIxA r=0.46 (p<0.001); RIxPI r=0.889 (p<0.001), PDxT r=0.490 (p<0.001) respectively.ConclusionsThere are other parameters in spectral Doppler to be validated in order to characterise changes in nail beds.Reference[1] Mendonça JA. High Specificity of Spectral Nail Assessment in Psoriatic Arthritis Patients [abstract].Arthritis Rheumatol. 2015;67(suppl 10).Disclosure of InterestNone declared
