ResumoIntrodução: A metastização óssea associa-se, geralmente, a mau prognóstico, com evidência de doença neoplásica avançada. Este estudo caracteriza uma amostra de doentes com metastização óssea e neoplasia primária conhecida, comparando com doentes sem neoplasia diagnosticada previamente. Material e métodos: Estudo observacional retrospectivo, onde foram incluídos doentes com diagnóstico de "neoplasia óssea secundária" ou "metástases ósseas", admitidos no nosso hospital, de 2009 a 2013. Analisados os dados de doentes com metástases ósseas com neoplasia primária conhecida ou oculta. Resultados: Incluídos 94 doentes, média de idades de 69±12. 66anos, 68% do sexo masculino. Os sintomas apresentados eram principalmente dorso-lombalgia (34%) e défice de força muscular dos membros (15%). Eám 42% dos doentes, existia previamente o diagnóstico de neoplasia. A coluna vertebral constituiu o principal local de metastização. Em 22% dos doentes não se identificou a neoplasia primária. A taxa de mortalidade durante o internamento foi de 14%, e no follow-up após um ano de 31%. Discussão: No estudo efectuado, verifica-se que a mortalidade à data de alta do internamento em doentes com neoplasia conhecida é superior à dos doentes com neoplasia indeterminada, o que não se verifica no follow-up a 1 ano. Pode considerar-se que os doentes com neoplasia previamente conhecida podem apresentar metastização óssea mais tardia, e assim, com pior prognóstico. Conclusão: A disseminação tumoral com expressão através da metastização relaciona-se com um agravamento do prognóstico no follow-up. Palavras-chave: metástases ósseas, coluna vertebral, neoplasia AbstractIntroduction and aims: The bone metastases usually have a bad prognosis, with evidence of advanced malignancy. This study evaluates the characteristics of patients with bone metastases and known primary neoplasia, comparing to those without previous diagnosed neoplasia. Material and methods: A retrospective observational study, was conducted to gather patients with diagnosis of "secondary bone cancer" or "bone metastasis", admitted to our hospital, from 2009 to 2013. Data from patients with known primary neoplasia, comparing to those with unkown origin neoplasia, were analyzed. Results: Ninety four patients were included, mean age 69+12. 66 years, 68% male. The symptoms were mostly back pain (34%) and limbs muscle strength deficits (15%). In 42% of them, there was a previous diagnosis of neoplasia. The spine was the primary site of metastasis. In 22% of patients, the primary tumor was not identified. The mortality rate during hospitalization was 14%, and 31% at one year follow-up. Discussion: In the study carried out, mortality at the end of hospitalization in patients with known neoplasia was higher than that of the patients with unkown neoplasia, which is not maintained at one year follow-up. Therefore, later presentation as bone metastasis in patients with known neoplasia, could confer a worse prognosis. Conclusion: The tumor spread with presentation through bone metastases, appe...
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