Every day have been increased the number of patients in the dental office looking for oral reabilitações, many of them being a challenge to the dentist surgeon. Currently, implants are installed on guided bone regeneration, the use of membranes, titanium threads and bone substitutes are key parts for correcting bone defects and to support the implant. Thereunto, the aim of this study was the description of a case addressing the methods and materials used for guided bone regeneration with the use of L-PRF for vertical bone gain. The patient showed the absence of the elements 22, 23 and 24, and a bony defect arc in this region. The installation of the implants, followed by guided bone regeneration support with a titanium mesh was indicated. The use of guided bone regeneration technique involving the mesh titanium implants, bone and lyophilized bovine L-PRF membrane showed a viable technique, the succeeding vertical bone gain until the implant platform.