Systemize the evidence of pulmonary ultrasound (PU) use in diagnosis, monitorization or hospital discharge criteria for patients with COVID-19. Systematic review of evidence which utilized PU for diagnosis, monitorization, or as hospital discharge criteria for COVID-19 patients confirmed by RT-PCR between December 1st of 2019 and July 5th of 2020 compared with thoracic radiograph (TR), thoracic tomography (CT) and RT-PCR. Type of study, motives for PU, population, type of transducer and protocol, results of PU, and quantitative or qualitative correlation with TR and/or CT and/or RT-PCR were evaluated. Were evaluated 28 articles with 418 patients. Average age 50 years (SD 25.1 years), 395 adults and 23 children. 143 were women, 13 pregnant women. The most frequent result was diffuse, coalescent and confluent B-lines. The plural line was irregular, interrupted, or thickened. The presence of subpleural consolidation was noduliform, lobar, or multilobar. There was good qualitative correlation between TR and CT and a quantitative correlation with CT of r=0.65 (p<0.001). 44 patients were evaluated only with PU. PU is a useful tool for diagnosis, monitorization, and criteria for hospital discharge for patients with COVID-19.

With the circulation of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC), there is a worry that an increase in transmission, hospitalisations, and deaths may occur efficacy of some vaccines may be compromised. Recently the WHO has recommended the use of labels with letters of the Greek alphabet. Then, the variants of concern are now called Alpha, Beta, Gamma, and Delta. So that the classification of the variants is more accessible and more practical when they are discussed in non-scientific audiences. In addition, the variants can be classified into three large groups according to their clinical capacity to affect global public health: variants of interest (VOI), variants of concern (VOC), and High consequence variant (VOHC). This review aims to explore the molecular and epidemiological characteristics of SARS-CoV-2 mutations and variants.

La infección por SARS-CoV-2 es la enfermedad emergente más importante del presente siglo. Desde su aparición hasta la actualidad ha ocasionado casi un millón de muertes en todo el mundo, convirtiéndose en una verdadera amenaza para la salud pública. Por tal motivo las nuevas revisiones y estudios científicos al respecto resultan sumamente importantes. De igual manera se sabe que la afección principal por este virus está confinado al sistema respiratorio. Sin embargo, aún existen aspectos desconocidos de la enfermedad y dentro de ellas se encuentran las complicaciones extrapulmonares. La presente revisión intenta resumir todo lo conocido al momento respecto a la enfermedad y sus complicaciones neurológicas, hematológicas. cardiológicas, renales y hepáticas.

The disease caused by the SARS-CoV-2 virus (COVID-19) can manifest itself through more than 80 symptoms and signs, considering it a multisystemic disease. 1 However, the disease is classified according to the pulmonary involvement evaluated through the measurement of the respiratory rate, respiratory signs and symptoms, oxygen saturation (SatO 2 ), the ratio of arterial oxygen pressure to inspired oxygen fraction (PaO 2 /FiO 2 ), and the extent of lung lesions seen on non-contrast chest tomography. The leading cause of death among patients with severe and critical COVID-19 is diffuse alveolar damage, a histopathological manifestation of Acute Respiratory Distress Syndrome (ARDS). 2

The objective of this study was to evaluate the role of Blastocystis sp. in gastrointestinal symptoms reported by adult patients in a Peruvian hospital. A case-control 3:1 study was performed at the outpatient clinic. Direct stool examinations were done. One hundred sixty patients were included, 40 cases and 120 controls. Positivity to Blastocystis sp. was associated with dyspepsia ( P <0.001), bloating ( P <0.001) and abdominal pain ( P = 0.03) in patients attending our hospital outpatient clinic.