A practical and highly stereoselective iron-catalyzed cross-coupling reaction of stereodefined enol carbamates and Grignard reagents to yield tri- and tetrasubstituted acrylates is reported. A facile method for the stereoselective generation of these enol carbamates has also been developed.

Apractical and highly stereoselective iron-catalyzed cross-coupling reaction of stereodefined enol carbamates and Grignard reagents to yield tri-and tetrasubstituted acrylates is reported. Afacile method for the stereoselective generation of these enol carbamates has also been developed.Supportinginformation and the ORCID identification number(s) for the author(s) of this article can be found under http://dx.

The FeCl3‐catalyzed cross‐coupling of E‐ and Z‐enol carbamates with Grignard reagents is reported to yield tri‐ and tetrasubstituted acrylates with retention of configuration.