Factors associated with adverse reactions to BNT162b2 COVID-19 vaccine reported by hospital workers are unclear. Our aim was to collect all reported adverse events in a cohort of hospital workers and to analyze the factors associated with their presence. We conducted an observational longitudinal study on all hospital workers of our center who received COVID-19 vaccination from 27 December 2020 to 1 September 2021. Information on adverse events was reported telephonically and confirmed through clinical records. Chi-square and t tests as well as multivariate logistic regression models were used. Cluster analysis was designed to explore associations between reactions. A total of 3969 hospital workers were included in the sample. Of the total sample, 182 workers (4.6%) reported adverse events. The most frequent symptoms were general malaise (n = 95), fever (n = 92), arthromyalgia (n = 80), and headache (n = 47). The factors associated with adverse events in adjusted analyses were an antecedent of COVID-19 infection (OR = 2.09, 95% CI: 1.47–2.98), female sex (OR = 1.51, 95% CI: 1.03–2.20), and professional category (OR for physicians = 0.41, 95% CI: 0.21–0.80). We report a low frequency of adverse events in hospital workers after COVID-19 vaccination and no severe reaction. Men and physicians underreported their symptoms. These data should guide future strategies for recording adverse events and future research on COVID-19 vaccination safety.
A case of follicular mucinosis (FM) after herpes zoster infection (VZV), which can be considered an epithelial reaction pattern defined by follicular mucin accumulation due to different triggers, is presented.A 59-year-old woman, with no personal history of interest, attended to our outpatient dermatological clinic complaining pruritic lesions on the neck and left supraclavicular area for 2 months. A 3 months before, the patient had had a VZV in that location (Figure 1A), persisting postherpetic neuralgia. Physical examination revealed monomorphic erythematous papules confluent in plaques, distributed over the area of left C3-C5 dermatomes (Figure 1B,C). Laboratory test including blood count cell test, general biochemistry, and autoimmune analysis (autoantibodies, immunoglobulins and complement) were within normal limits. Histological findings showed perifollicular dermatitis with
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