This review discusses those factors that have an influence on amine concentration in wine, as well as the vinification stages when these amines are formed and their evolution during the storage of the product. It also outlines the importance of these biogenic and volatile amines both in the sensorial aspect as well as the toxic action. Amines are nitrogenous bases of low molecular weight, which are especially found in food and beverages from the fermentation process, as is the case of wine. Amine concentration in wine can be very variable, ranging from trace levels up to 130 mg/L, so it is difficult to predict the content of these compounds in the product. At present this variability is of some concern in many countries, especially for the toxic effect that some amines can have on people who are susceptible to these substances. Consequently, it is necessary to develop new studies to learn more about the factors, which have an influence on their concentration in wine, and to establish limits for these substances in the product so as to prevent any toxic effects on the consumer.

Several factors can affect production of volatile compounds in wines, including nutritional differences in the must. Among the nutritive compounds of must, the amino acids are of great importance due to the fact that they can serve as precursors of esters or may play an indirect role in supporting cellular metabolic activities. The aim of this study was to examine the influence of the addition of a complex nutrient such as the yeast autolysate to a nitrogen nonlimited must of Chardonnay variety on the formation of esters, alcohols, and acids. Yeast autolysate supplied fatty acids, amino acids (above all, tyrosine, threonine, and glutamic acid), and an insoluble fraction formed by yeast cell walls. It was observed that the nutrient enrichment of the Chardonnay must did not favor the formation of either esters or alcohols. These results demonstrate that when juice is sufficient in nitrogen, the addition of amino acids does not improve the volatile composition of wine. Under these conditions, the amino acids would have probably been used for other cellular processes that do not produce volatile compounds.

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Some white wines of Chardonnay variety are aged on their lees in oak barrels over several months. Over this period, autolysis takes place and different compounds are freed in the wine, among them, nitrogen compounds. The aim of this work was to study the evolution of amines in Chardonnay wine during 180 d of maturation on lees, with and without weekly stirring. The process was carried out in new French oak barrels with 225 L capacity. From the results obtained it was found that weekly stirring mainly had an influence on histamine and tyramine concentration. The concentration of these amines at the end of the aging period was higher in the wine with weekly stirring. This treatment showed no effect on the amine concentration at the beginning of the wine aging on lees. The aging time also had an influence on the concentration of amines in the Chardonnay wine.