Backgroud: Epilepsy is a chronic, recurrent disease, characterized by paroxysmal changes in intellectual, sensory, motor, autonomic or affective activity, with limited time. Objectives: To analyze cases of hospitalizations and deaths between 2010 and 2019 in Brazil. Methods: Descriptive epidemiologic study using data from the Department of Information of the Brazilian Health System (DATASUS). The variables researched were: hospital admissions, death, brazilian regions, age group, gender and race. Results: It was accounted 196,351 hospitalizations, 52% in the Southeast, 25% in the South, 14.7% in the Northeast, 5% in the Midwest and 3.1% in the North. In relation to profile, the male gender (59.9%) constituted the majority. In the case of deaths, 12.723 males and 6.557 females were reported, of which 46,4% were white and 41,8% were brown race. Major part of the deaths, 41,9% happened in the Southeast. The most affected age group was between 40 and 49, with 20.5% of cases. Conclusions: Therefore, most hospitalizations and deaths occurred in men, aged between 40 and 59 years, of white race, residents of the Southeast region.