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A large screening of around 1000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogotá, Colombia. After a simple generic solid-phase extraction (SPE) step with Oasis HLB cartridges, analyses were made by ultra high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UHPLC-QTOF MS) under MS E mode (sequential acquisition of mass spectra at low energy (LE) and high collision energy (HE)). Accurate-mass measurements and the information provided by MS E on the presence of the

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