Objectives: Benzodiazepines (BZ) are widely prescribed drugs, but Objectives: Benzodiazepines (BZ) are widely prescribed drugs, but Objectives: their use is controversial in patients who present a disorder caused by substance use/abuse, due to the risk of tolerance and abuse/dependence. The purpose of this work is to determine the levels of BZ use in patients treated with methadone and to compare them with findings from the current literature. Methodology: a sample of 43 patients was selected; inclusion criterion was being on the PTDO (treatment program with opiate derivatives) at the UAD (Drug-dependence unit) in Monforte de Lemos (Lugo-Spain). Demographic and use variables were analyzed. Data collection and subsequent analysis were carried out using the statistical program SPSS 12.0. Results: 46.5% of the patients take BZ, and of these, 60% are over age 45. The most widely used of these is alprazolam (p < 0.001), and 70% take just one active ingredient. The main prescriber is the general practitioner, and the most frequent indication is insomnia. Discussion and Conclusions; BZ-use data and their relationship to time Discussion and Conclusions; BZ-use data and their relationship to time Discussion and Conclusions; spent on methadone are similar to those of other published studies. Despite the recommendation to use long half-life BZ in patients with substance abuse disorders, it is striking that in the case studied here the most widely prescribed type is alprazolam. RESUMEN ABSTRACTObjetivos: Las benzodiacepinas (BZD) son fármacos ampliamente prescritos, pero su utilización es controvertida en pacientes que presentan un trastorno por uso/abuso de sustancias debido al riesgo de tolerancia y abuso/dependencia. El objetivo de este trabajo es determinar la utilización de benzodiacepinas en los pacientes a tratamiento con metadona y compararlo con la literatura existente. Metodología: Se ha seleccionado una muestra de 43 pacientes cuyos criterios de inclusión fueron estar en PTDO en la Unidad Asistencial de Drogodependencias (UAD) de Monforte. Se analizaron variables demográficas y de consumo. La recogida de datos y el posterior análisis se ha realizado mediante el programa estadístico SPSS 12.0.Resultados: El 46,5% toman benzodiacepinas y de éstos el 60% es mayor de 45 años. La más usada es alprazolam (p < 0,001). El 70%, toman un único principio activo. El principal presciptor es el médico de cabecera y la indicación más frecuente es el insomnio. Discusión y conclusiones: Los datos de consumo de BZD y su relación con el tiempo de permanencia en metadona son similares a los de otros estudios publicados. A pesar de la recomendación de utilizar en pacientes con trastorno por abuso de sustancias BZD de vida media larga, resulta llamativo que en nuestro caso la más prescrita sea alprazolam.Palabras clave: benzodiacepinas, metadona, indicación, prescripción, uso/ abuso.
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