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Introduction Manual Lymphatic Drainage (MLD) creates pressure differentials to promote the movement of lymph and interstitial fluid, for their relocation into the bloodstream and can thus act on the variables responsible for determining blood pressure (BP). Objective To investigate the behavior of hemodynamic parameters, such as BP and Heart Rate (HR) during and immediately after a session of MLD. Materials and methods 23 healthy young volunteers with a mean age of 22 ± 2.97 years (18-29), underwent a session of MLD and evaluation of systolic BP, diastolic BP and HR after 10 minutes of initial rest, at the end of the implementation of the protocol in SP, PP and after 15 minutes of final rest. Results No changes were found in systolic BP or diastolic BP before, during and immediately after the MLD session (p = 0.57, p = 0.20, respectively). There was increased heart rate after the final 15 minute rest when compared to the HR after MLD in SP (72 ± 1.9 vs. 76 ± 1.9, p = 0.002), however, without clinical relevance. Conclusion During a session of MLD with healthy young women, no significant hemodynamic changes occurred, demonstrating that this technique is safe from the cardiovascular point of view.

Before the arrival of Spanish settlers, the East region of Paraguay, was inhabited by Guarani people. After the Paraguayan war in 1870, which ended in loss of a high percentage of the male population, the migration to the country was encouraged. Immigration data indicate a high input of Eurasians to the territory. Also, since 1960s, a large number of Brazilians and Argentineans arrived in Paraguay. Samples from the eastern provinces of Paraguay were sequenced for the mtDNA control region and 88% presented native American haplogroups. A preliminary study on the same samples using AIMs indicates a high autosomal contribution from Europe and native America. The comparison of both type of markers showed that the European ancestry for autosomes is higher than expected when averaging mtDNA and the Y chromosome. This result supports recent admixture between Paraguayans and other populations probably already admixed, where the men contributed with high European ancestry.