Currently, companies have increasingly needed to improve and develop their processes to flexible the production in order to reduce waiting times and increase productivity through smaller time intervals. To achieve these objectives, efficient and automated transport and handling material systems are required. Therefore, the AGV systems (Automated Guided Vehicle) are often used to optimize the flow of materials within the production systems. In this paper, the authors evaluate the usage of an AGV system in an industrial environment and analyze the advantages and disadvantages of the project. Furthermore, the author uses the simulation software Promodel ® 7.0 to develop a model, based on data collected from real production system, in order to analyze and optimize the use of AGVs. Throughout this paper, problems are identified as well as solution adopted by the authors and the results obtained from the simulations.

Schimmelpenning syndrome (SS) includes an organoid nevus that follows the lines of Blaschko and defects of brain, eyes, bones, or other systems.We report a case of a 3-month old female infant, who presented with several thin plaques, with irregular borders, yellowish color, which had a verrucous appearance, following the lines of Blaschko, mainly occupying the left side of posterior trunk, the left face, the right side of the anterior trunk, and the right upper limb. These plaques had been present since birth. In addition, she had a flat salmon to yellow nevus on the left parietal and temporal region of the scalp, with a bald patch. She was diagnosed after birth with an interauricular communication.The skin biopsy from the lesion of the right arm revealed an epidermal nevus that occupied the epidermis completely. Routine and other complementary laboratory blood tests, including platelet count, thyroid function tests, 25-hydroxy-vitamin D, parathyroid hormone, and plasma and urinary levels of calcium and phosphorus were negative. Cerebral magnetic resonance and renal ultrasound were normal. The diagnosis of SS was established.She is being followed in the clinics of Dermatology, Cardiology, Pediatrics, and Pediatric Neurology. We report this case to point out the importance of investigating patients with epidermal nevus to identify associated conditions

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BACKGROUNDAdvances in knowledge about immune-mediated myopathies (IIMs) demonstrate that many patients previously classified as having polymyositis (PM) could have an alternative diagnosis. The differential diagnosis for a suspected case of PM includes muscular dystrophies, metabolic, congenital or infectious myopathies, lower motor neuron disease and myasthenia gravis.

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