ResumoObjetivo: Analisar a idade na cirurgia de crianças com atresia biliar e a sobrevida sem necessidade de transplante de fígado. O estudo foi realizado no Hospital de Clínicas de Porto Alegre. of cases, the age was below 60 days. There was no age difference at diagnosis for the three decades in the study. Patients from the countryside (median: 87.0; IQR25-75: 69.0-115.0 days) were referred significantly later (p = 0.007) than those living in Porto Alegre and the metropolitan area (median: 68.0; IQR25-75: 55.5-98.0 days). The ratio of patients younger than 60 days was significantly lower (p = 0.013) for those from the countryside. Survival periods with native liver for all patients was 46.2% in 2 years, falling continuously until reaching 15.3% in 20 years. Patients operated before reaching 60 days of age had longer survival periods with native livers (log rank < 0.0001). MétodosConclusions: Late performance of portoenterostomy was a constant in the past 25 years, and this delay led to shorter survival periods with native livers for biliary atresia patients.J Pediatr (Rio J). 2008;84(5):436-441: Biliary atresia, neonatal cholestasis, surgery, prognosis, survival. IntroduçãoA atresia biliar (AB) é a doença hepática crônica que mais freqüentemente afeta as crianças e é a causa mais comum de colestase neonatal. Sua etiologia permanece desconhecida e provavelmente resulta de um processo heterogêneo em que o insulto inicial, seja infeccioso, isquêmico ou tóxico, precipita a destruição inflamatória progressiva dos ductos biliares nos pacientes geneticamente suscetíveis 1 . A AB tem distribuição universal, e estima-se que afeta 1 em cada 5.000 a

Red blood cells transfused (ml/Kg) 73.4 ± 102.38 35.1 ± 41.67 0.040 Reoperation due to bleeding in the wound area 10 (55%) 3 (17.6%) 0.035 Biliary leak in the wound area 2 (11.1%) 3 (17.6%) 0.65

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LINHARES, A. L. F. A. Detection of anabolic androgenic steroids and its biotransformation products in dried urine spots by paper spray-mass spectrometry ionization (PS-MS). 2020. 142f. Dissertação (Mestrado em Farmácia -Fisiopatologia e Toxicologia) -