Case series summaryTwo cats with a marginally resected eyelid malignant peripheral nerve sheath tumour were treated with adjuvant strontium plesiotherapy a few weeks after surgery. The dose applied in both cases was 200 Gy to the surface, in five fractions, on a Monday–Wednesday–Friday basis. The treatment aimed to achieve a clinical margin of approximately 1 cm around the surgical scar and multiple application fields were required to cover such an area. Local recurrence was not seen in either case after 1330 and 645 days, respectively.Relevance and novel informationThe majority of periocular malignant peripheral nerve sheath tumours reported in the literature recur after surgery. In the two cases described in this report the combination of surgery and adjuvant plesiotherapy has been able to provide good local control with minimal toxicity. This multimodal approach could be considered as an alternative to aggressive surgery such as enucleation or exenteration.
Objectives
To determine the owners’ perception of dogs' quality of life before, immediately after and 6 weeks after radiotherapy treatments for a variety of neoplasms and assess owner satisfaction over their decision to treat.
Materials and Methods
Questionnaires were given to owners whose dogs completed a radiotherapy treatment at a referral radiation oncology centre. Questionnaires were given at three time points: before treatment, on the last day of treatment and more than 6 weeks after the treatment was finished. Owners were asked questions regarding their perception of radiotherapy and the quality of life of their pets before, during and after treatment with radiation therapy. Quality of life was scored from 1 (could not be worse) to 10 (could not be better).
Results
Seventy‐one owners met the inclusion and exclusion criteria. Results showed that 6 weeks or more after treatment, most owners were happy that they had chosen to treat their dogs (92%) and would treat another pet again, if indicated (88%). Across the three time points, median quality of life perception score was 9.
Clinical Significance
Radiotherapy was well tolerated by owners and dogs in this study. The great majority of clients were happy to have pursued radiotherapy, would choose to do it again (if indicated) and would recommend it to a friend.
Two cases of lipomatosis of the parotid salivary gland in two dogs are reported. Both dogs were presented with a slow growing unilateral non-painful mass in the parotid region. The mass measured 12 and 15 cm on the longest axis for case 1 and 2 respectively. Initial incisional biopsies were suggestive of infiltrative lipoma or salivary gland adenocarcinoma. Case 2 underwent head radiographs that showed a soft tissue opacity on the area of the right parotid gland followed by a computed tomography that showed a multi-lobulated infiltrative mass occupying the right parotid gland. Both cases underwent total parotidectomy with an excisional biopsy intent. Surgery on case 1 included total ear canal ablation (TECA). Histology revealed lipomatosis of the parotid gland with a similar admixture of adipocytes and well-differentiated salivary acini on both cases. No recurrence was reported by 4 years for case 1 and by 3 years for case 2. Case 1 developed long-term right-sided facial paralysis and palpebral reflex deficit due to damage of the facial and trigeminal nerve during surgery. The cases are described and the veterinary literature is reviewed in view of the most updated information available in human medicine on fat-containing salivary gland lesions. Considering this literature review, authors recommended these two cases to be classified as lipomatosis of the salivary gland. In conclusion, fat-containing salivary gland lesions should be considered in the list of differential diagnoses in dogs with an enlarged salivary gland and seem to be associated with an excellent prognosis after surgical excision.
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