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The aesthetic experience has been discussed throughout the history of mankind by philosophers and art historians, becoming a universal part of human experience, which leads us to some great interdisciplinary questions. It has been the subject of study by neuroscientists and neuro-psychologists since the 2000s. This recent evolution of neurology studies in the field of art, is due to in vivo brain imaging techniques, especially functional neuroimaging. Furthermore, recent research has provided evidence of cognitive interaction during the perception of an artwork indicating that the perceptual experience of art is not merely a passive one. This article reviews important studies in neuroaesthectics of visual art that point out that the aesthetic experience is related to the distribution in the neural architecture, suggesting the involvement of sensory-motor areas, emotional centers, reward system, memory and language.