Background: The oral mucosa and tongue constitute a barometer, a mirror reflecting the state of health of patient. Similar to skin, lesions in mouth speak for itself. They often provide unique opportunity to understand systemic disease process. With careful and judicious practice many systemic diseases can be identified through the manifestations present in oral cavity. It is in light of this that it was thought proper to carry out a prevalence study of some of commonly occurring oral lesions in a skin, STD/HIV and leprosy OPD. Aims and Objectives : This study was undertaken to find the prevalence of oral lesions related to dermatoses, sexually transmitted diseases (STD) and Human Immunodeficiency Virus (HIV) infection in outdoor patient department (OPD) with reference to number of cases, age and sex distribution.To determine percentage of symptomatic and asymptomatic patients among those with oral lesions.To analyze into various groups the oral pathologic conditions.To determine the local co-factors for oral lesions, if any. Methodology: The study was carried out in a cohort of 300 new patients attending the Skin, STD and HIV OPD of a teaching hospital in Department of Skin and V.D. in a Tertiary care centre. All new patients attending the OPD, irrespective of age, sex and presenting complaints were entered in the study. Results: Out of 300 patients studied 183 (61%) were male and 117 (39%) were females. Majority of patients belonged to age group 20 to 40 years. Out of 116 patients found to be having oral lesions only 15 (13%) had oral symptoms. 116 (38%) were having oral lesions of which 82 (27%) were males and 34 (11%) were females. Pigmentary disorders, carries and white deposits like candidiasis were much more common in males whereas lichen planus was more common in females.

Background: Pemphigus is a group of rare, chronic, autoimmune, potentially fatal vesiculobullous diseases of the mucous membranes and skin. Clinical profile and epidemiologic characteristics varies in different parts of the world. Aim: The aim of this study was to evaluate the clinical and epidemiological features of pemphigus in our hospital and to compare the results with those in the literature. Methods: All newly registered patients with confirmed pemphigus admitted at the Department of Dermatology between the period August 2009 and July 2015 were evaluated. Demographic variables and clinical presentation, treatments received were recorded. Results: Out of 91 patients diagnosed as pemphigus in our centre during the period of 6 years pemphigus vulgaris was the most common type (91.2 %). The mean age of onset was 45 years. Male to female ratio in the patients with pemphigus vulgaris was 1: 1.5. Oral lesions were found in 84 % of patients and it was the first manifestation in 66%. Mortality rate was 1% (2 cases) which was due to sepsis. There was no mucosal involvement in patients with pemphigus foliaceus. Only 1 patient had a positive family history. No seasonal predominance for the onset of the disease was noted. Conclusion: Pemphius vulgaris is the predominant form of pemphigus seen followed by pemphigus foliaceus. Oral mucosa as well as skin are the major sites of involvement. Due to increase in life expentancy occurance of Pemphigis is not an uncommon condition in elderly individuals.

Actinomycosis is a chronic suppurative granulomatous infection of subcutaneous tissues caused by bacterium Actinomyces israelii. It is a normal commensal of the oral cavity, gastrointestinal tract, respiratory tract, and vagina. Infection is first established locally by breach of mucosal barrier during various procedures, aspiration, trauma, or human bite. Rarely, it may spread through hematogenous and lymphatic system. We present a case of actinomycosis involving the vulva, extending to the inguinal region along with inguinal lymphadenopathy. Involvement of vulva by actinomycosis is uncommon in literature.

Psoriasis is a chronic papulosquamous disorder presenting with erythematous, pruritic plaques, silvery-white scales and ssures. Eczema is characterized by hyperkeratotic plaques associated with scaling, occasional oozing and pruritus. Palmoplantar psoriasis and palmoplantar eczema have close resemblance in their clinical presentation and hence, pose a difculty in diagnosis. Dermoscopy of palmoplantar psoriasis predominantly shows light pink-red background, diffuse white scales, regularly distributed dotted vessels while eczema predominantly shows yellow scales, linear and dotted vessels on a dull red background along with brown dots and globules. In this study, we found that both palmoplantar psoriasis and palmoplantar eczema have distinct dermoscopic ndings and thus, dermoscopy is an effective and noninvasive way to differentiate the two conditions

Background: Acne scars are most distressing sequelae of acne vulgaris having a major impact on psychosocial aspect and quality of life of an individual. In spite of various therapeutic modalities available treatment of acne scars is challenging. Resurfacing techniques such as Fractional Co2 Laser is a well-established treatment option for acne scar. Platelet-Rich Plasma (PRP), an autologous preparation of growth factors helps in wound healing and tissue regeneration. Aim: To study the efficacy of Fractional CO2 Laser with Topical Platelet-Rich Plasma in Acne scars. Materials and Methods: A total of 15 patients with atrophic facial acne scar, aged 18-40 years attending Outpatient Department of Dermatology, Venereology and Leprosy at tertiary care centre during January 2019 to December 2019 were included for this interventional study after written informed consent. The patients underwent six sessions of Fractional CO2 Laser with Topical application of Platelet-Rich Plasma at monthly intervals. Pre and post treatment comparative Goodman and Baron’s quantitative global scarring grading and patients self-assessment score were used for assessment. Results: At the end of study mild reduction in Goodman and Baron’s quantitative score for acne scar was noted in 13 patients (86.6%). Mean Goodman and Baron’s quantitative score att 4 weeks after sixth sitting was 13.13 ± 4.60. On patients self-assessment moderate resolution of acne scar was noted in 8 patients (53.3%). Conclusion: Fractional CO2 Laser with Topical Platelet-Rich Plasma application has mild to moderate improvement of acne scars and shorter down time of Fractional CO2 Laser. Keywords: Acne scar, Fractional Co2 Laser, Topical Platelet-Rich Plasma