Immune thrombocytopenia (ITP) can be rarely associated with pregnancy. The management of ITP during pregnancy is a contentiou s issue and is often decided by a multi-disciplinary team. We here present a case of a 20-year-old female presenting with ITP in pregnancy. She was managed initially with oral prednisolone followed by IVIg (1 g/Kg) near term. The platelet counts increased significantly after the single dose of IVIg and she underwent a caesarean section at 37 th week uneventfully. Platelet count of the neonate was also normal. Relevant literature on the use of IVIg for this and other indications during pregnancy have also been discussed.

L-arginine is a unique molecule that produces nitric oxide in body and plays a crucial role in physiological hemodynamic modification in pregnancy. A randomised comparative prospective study was carried out in a maternity hospital in Kolkata over one year. The study involved a study group of fifty antenatal mothers with asymmetrical fetal growth restriction detected ultrasonographically around 30-32 weeks of gestation and treated with 5 grams of L-arginine per day over a period of 28 days and a historical control group of fifty patients of same parameters with non-ambulatory treatment in home atmosphere. The aim of our study was to compare the fetal growth and pregnancy outcomes in pregnant mothers supplemented with L-arginine with that in the control group with non-ambulatory treatment in home atmosphere. L-arginine was found to accelerate fetal growth. Fetal growth restriction at delivery in L-arginine group was 42% compared to 46% in control group (p=0.84). Moreover, neonates of treatment group revealed higher Apgar score, lower incidence of respiratory distress syndrome (16% versus 42%, p=0.0076) and intraventricular haemorrhage (2% versus 20%, p=0.007) and lower admission to neonatal intensive care unit (10% versus 44%, p=0.000225). Caesarean section rate was higher in control group than in arginine group (80% versus 72%, p=0.48). Hence, oral treatment with Larginine seemed promising in improving fetal outcome.