Background: Surgical mortality data are collected routinely in high-income countries, yet virtually no low-or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergency abdominal surgery, comparing findings across countries with a low, middle or high Human Development Index (HDI).Methods: This was a prospective, multicentre, cohort study. Self-selected hospitals performing emergency surgery submitted prespecified data for consecutive patients from at least one 2-week interval during July to December 2014. Postoperative mortality was analysed by hierarchical multivariable logistic regression.

In the past few decades, developing antifungal and anticancer agents has become essential in drug research. Cancer is one of the most challenging diseases in the world. Most reviews on chalcones suggested that substituted chalcones have numerous biological activities. This study aim includes synthesizing different Sulphur containing chalcones in the presence of para-amino acetophenone linked to various aldehydes in the presence of aqueous alcoholic alkali. The structural analysis of synthesized compounds was also carried out by IR, 1HNMR 13CNMR and MASS spectra. The docking study was performed by Biovia discovery studio 20202. Invitro cytotoxic activity was carried out by human breast cancer cell line MCF-7 using MTT assay. Antifungal activity was conducted by diffusion method against Candida albicans and Aspergillus niger. Novel synthesized compounds, especially BT-IV-A, BT-IV-B, BTIV- C, BT-IV-E and BT-IV-I showed significant antifungal activity as BT-IV-H, BT-IV-E, and T-IV-F revealed excellent growth-inhibitory impact for the development of new anticancer agents.

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Background: Pulmonary function tests are widely used as a valuable diagnostic tool in detecting and diagnosing various respiratory disorders like COPD, they also play an important role in monitoring therapy effectiveness and course of the disease. Normative values of pulmonary functions of healthy population are affected by different geographic, ethnic, climatic and demographic factors. The most important determining factors of Vital capacity in an individual are anthropometric factors such as age, sex, height, weight, body mass index (BMI) and body surface area (BSA) Aims and Objectives:The aim of the present study was to find the correlation between Forced Vital Capacity (FVC) and anthropometric measurements like height, weight, body mass index (BMI) and body surface area (BSA) in Indian adult males.Materials and Method: Fifty healthy adult males were randomly selected for the study. Ethical clearance was taken from the Institutional Ethical Committee. The physical factors namely height, weight, body mass index (BMI), and body surface area (BSA) were measured. FVC was recorded by using computerized spirometer. The correlation between the various physical factors and FVC was done using Pearson's correlation.Results: Height, weight and body surface area showed significant positive correlation with FVC. However height showed the strongest correlation (r = 0.5807), followed by BSA (r = 0.531) and lastly weight (r = 0.422). However the correlation of BMI with FVC was not statistically significant. Conclusion:The present study showed that body height, body surface area and body weight are important determinant of FVC in Indian adult males, with height being the most important determinant.