Food allergy is a primary cause of early manifestations of atopic disease. House dust mites are the main aeroallergens that underlie allergic manifestations. Both of them play a role in the pathogenesis of atopic diseases and cause an impact on the family’s economy and health costs. This study was a consecutive sampling retrospective cohort with house dust allergy as an independent variable; food allergy with and without dust allergy with allergenic food elimination, sign & symptom score, medication score, combination sign & medication score, visit fee outpatient care, inpatient costs, and total medical expenses as the dependent variable. Data were collected using secondary data from medical records or patient reports via mobile phone messaging applications every month. We averaged data at 3, 6, 9, and 12 months after the patients were diagnosed with food allergies and undergoing a food elimination diet. The data were analyzed using the Kruskal-Wallis test with a significance level of <0.05. We can conclude that house dust allergy influences allergenic food elimination diet effectiveness (p=0.001).