This review is an attempt to consolidate the earlier studies on this subject and to get a broad based idea if there exists any relationship between full moon and various physiopsycological aspects on human like behavior, sleep cycle, cardiovascular system, endocrine system, birthrate, reproductive system. MethodologyData were collected from review of literatures from various scientific studies conducted so far globally. To meet our objectives, we try to do a study and see what actually occurs in the human body during full moon. To find out the related up-to-date topics we searched through PUB Med central, Goggle Scholar and related bibliographic databases. Only peer reviewed articles were chosen which were supposed to be of high quality. Database was created in the Endnote software and full text articles were collected by Endnote software. If there was a lack of information we contacted the corresponding authors for further clarification.