<p><strong>Objective. </strong>Gardner’s syndrome is a variant of familial adenomatous polyposis, characterized by gastrointestinal polyps, multiple osteomas, and skin and soft tissue lesions. Diagnosis by means of an understanding of its various symptoms is of great importance.</p><p><strong>Case report. </strong>This report presents the case of a 32-year-old man with obvious asymmetry and disfigurement on his face, due to multiple osteomas and soft tissue lesions. These clinical signs prompted us to further investigation, leading to the diagnosis of a case of Gardner’s syndrome, with asymptomatic polyposis of the colon. Polyps have virtually an almost 100% risk of undergoing malignant transformation.</p><p><strong>Conclusion. </strong>Early diagnosis and treatment of this pathological entity are crucial, while the presence of osteomas should alert us to this diagnosis.</p>

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Background: Ancient Greek medico-philosophers comprehended a series of genitalia disorders and were able to perform surgical operations for their correction. Although researchers believe that the first plastic surgery of pseudo-hermaphroditism was performed by Persians in 11th century AD, a series of intersex individual cases were reported in the work of the ancient Greek historian Diodorus Siculus. Methods: Bibliographical study of Diodorus' treatises. Results: The report of a patient named Callo, who was raised as a female and was surgically transformed into a young male, was included in Diodorus' works. Diodorus described that the operation was performed surprisingly by a pharmacist, testifying the extent and depth of medical knowledge among ancient Greeks. The operation included cicatrization and placement of an artificial urethra in the non-perforated penis. Conclusions: The operation was for the era an innovative procedure ahead of its time, a hallmark of cosmetic and plastic surgery.