Psoriasis of the lips was observed in a 54-year-old female who had suffered from psoriasis vulgaris for 18 years. The psoriasis of the lips was preceded by protrusion of the upper teeth. Topical corticosteroid and later 5-fluorouracil treatment were ineffective. The disease recurred even after replacement of the vermilion by plain mucosa. The disease was successfully treated by replacement of the protruding teeth by a nonirritating prosthesis.
In 13 patients with psoriasis a lower total cholesterol (TC) concentration was found compared to healthy controls of the same population. No differences in the concentration of serum triglyceride (TG) or phospholipids (PL) were detected between these two groups. In the same patients, serum triglyceride fatty acid analyses showed a reduced concentration of linoleic acid and a raised level of palmitoleic and myristic acids. No differences were detected in the major phospholipid fractions. The increase in plasma free fatty acids (FFA) following intravenous heparin was comparable in the psoriatic patients and in the controls. It is concluded that no basic abnormality of serum lipids exists and that the changes described were due to a selective loss via the scales or due to malabsorption.
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