The kinetics of the reaction of OHwith 1,3,5-trinitrobenzene in the presence of dodecyl and hexadecyltrimethylammonium bromide have been studied. The micellar effects on this reaction have been modelized with the help of a new thermodynamic and kinetic analysis. This modelization has been based on a profitable approach proposed by De Donder and Defay which is well suited to the kinetics in dispersed medium. The chemical exchange rates σ V 0 and b V 0 , which are, respectively, the micellar and the bulk exchange rates, have been determined. This report also reveals that the acceleration of chemical reactions is mainly due not only to a large increase of the chemical exchange rate on the micellar aggregates but also to the high stabilization of the activated complex.