Abstract. Nugroho AA, Hikmayanti NH, Djumaga S. 2012. Effect of salam (Syzygium polyanthum) leaf extract to decrease blood triglyceride level on white rats. . This study aimed to determine the effect of bay [Syzygium polyanthum (Wight) Walp.] leaf extract to decrease the blood triglyceride level of white rats (Rattus norvegicus). This research was an laboratory experimental research with pre and post-test design with control group. This research used 30 Wistar white rats, with ±200 g body weight and the age of ±2 months, divided into 5 groups by a random sampling, six rats per group. Group I was a negative control, group II was a positive control, groups III, IV and V was treated with the bay leaf extract in the doses of I, II and III. All groups were fed of hyperkolemia, group II was treated by Gemfibrozil 20 mg/200 g BW/day, while groups III, IV and V were treated by the bay leaf extract with the doses of 0.18 g, 0.36 g and 0.72 g/200 g BW/day. The study was conducted for 35 days. On the 28 th and 35 th day, the blood of all rats was taken from orbital vein for blood triglyceride levels measured in pre-test and post-test. The data were statistically analyzed with One-Way ANOVA test and a post-hoc test. There were significant differences between pre-test and post-test in the levels of blood triglycerides of white rats (p<0.001), in which a post-hoc test results showed the comparison between negative control and Gemfibrozil was p<0.001, and the comparison between the groups of the bay leaf extract with Gemfibrozil was p>0.05, and the comparison of three doses of bay leaf extract was p>0.05. The provision of bay leaf extract could reduce the blood triglyceride levels of white rats significantly compared with the negative control, whereas the effects of three doses of bay leaf extract was comparable with the effects of Gemfibrozil. Berdasarkan penelitian sebelumnya oleh Dalimartha (2007) belum diketahui dosis yang efektif dari ekstrak daun salam, sehingga perlu dilakukan penelitian yang bertujuan untuk membuktikan potensi ekstrak daun salam dalam menurunkan kadar trigliserida darah, dan menetapkan dosis efektif dari perlakuan dosis bertingkat ekstrak daun salam.Dalam penelitian ini dipilih metode ekstraksi dengan maserasi karena lebih efektif dalam memisahkan zat-zat aktif pada daun salam yang digunakan sebagai penurun kadar trigliserida. Adapun pada penelitian sebelumnya hanya digunakan rebusan daun salam yang hasilnya kurang efektif karena masih tercampurnya zat-zat lain yang dapat mengacaukan hasil penelitian.Pada era globalisasi saat ini, kemajuan teknologi dan sistem informasi memungkinan orang dengan mudah mencapai tujuannya, antara lain adanya fasilitas layanan makanan cepat saji yang sangat tinggi lemak, tinggi kalori, dan rendah serat, penggunaan kendaraan bermotor, lift, serta remote control televisi, yang cenderung mengubah gaya hidup masyarakat (terutama di perkotaan) menjadi sedentary lifestyle. Apalagi dengan adanya tuntutan pekerjaan, membuat orang kurang dapat meluangkan waktu untuk berolahraga d...

Introduction: Placenta previa and morbidly adherent placenta cause significant maternal morbidity and mortality from postpartum hemorrhage. Intra-aortic balloon occlusion has been shown to reduce intraoperative hemorrhage effectively. Cases Presentation We reported four cases of women who underwent cesarean section and hysterectomy with IABO. All four were multigravida, gestational age range was 37-39 weeks, MAP score range 6-8. Ultrasound examination showed placenta accreta. After the cesarean section and hysterectomy procedure with IABO, the bleeding was 600-800 cc. Conclusions Intra-Aortic Ballooning Occlusion is an effective method to reduce bleeding complications during and after cesarean section in pregnancies with placenta accreta.

Introduction and importance Anterior chest wall Giant Basal Cell Carcinoma (GBCC) is rare amongst GBCC cases and results in a large defect that is challenging to resect and reconstruct. It requires multidisciplinary approach to prevent recurrence. Case presentation A 72-year-old man with giant basal cell carcinoma at the anterior chest wall measuring 10 × 6 cm. Wide resection of 1 cm margin with axial flap was performed to close the defect. The follow-up report stated that the patient was satisfied with the result and there was no recurrence observed. Clinical discussion Review of literatures concludes that GBCC is excised with a minimum of 4-6 mm margin outside the tumor area. The axial IMAP flap is ideal to close the upper chest wall defect because of the better aesthetic outcome compared to other conventional flaps, especially in stable elderly male, patients with noninfected wound. Increased skin laxity and more relaxed skin tension associated with aging allows easier tissue mobilization and transfer to close the defect. Conclusion Axial flap for GBCC in anterior chest wall is ideal, safe, and has the advantage of aesthetic reasons of suitable skin tone, particularly for stable elderly male patients.