Background:In the early lactation, dairy cows go through a period of negative energy balance because they do not intake enough food to supply the energetic demand of milk production. In this period, dairy cows are susceptible to metabolic disorders, although has little evidence that milk production contribute to increase diseases occurrence. Some alternatives to minimize metabolic disorders, that reduce milk yield, has been suggested, as increase energy density in the diet of dry cows 21 days before the parturition and include additives in the diet pre and post-partum. The aim of this study was to measure the productive parameters in dairy cows fed calcium salts as energetic source. Materials, Methods & Results:Two Latin square 4x4 were used, whereas one comprehended of early lactation cows and the other of mid lactation cows. Animals of 2 nd and 3 rd parity were used only. Parity was distributed evenly among groups. The trial consisted of 4 groups with 4 treatments as follow: T1: 300 g of calcium acetate, T2: 200 g of calcium propionate, T3: 200 g of calcium salts of fatty acids, and T4: control without any calcium additive. The animals were milked twice a day, the first milking at 07:00 am and the second milking at 05:00 pm. Milk samples were collected in plastic containers with potassium dichromate. These samples were sent to the Laboratory of Milk Analysis of the Paranaense Association of Breeders of the Holstein Breed for analysis of fat, protein, lactose and total solids through the infrared method. Throughout the experimental period, the daily production of the animals under study was recorded. The production of milk (kg) was corrected to 3.5% fat using the formula PLA 3.5% = (0.432 + kg milk) + (0.1623 x kg milk x fat content). Discussion: Greater supply of glucose or propionate stimulate milk protein production, but the mechanism of this stimulation is unclear. Milk protein is dependent on energy supply, and deficient energy intake reduces milk protein levels. Calcium propionate provided enough energy supply and increased milk protein levels. The synthesis of lactose has influence in water absorption in mammary gland and lactose determine milk osmolarity. The lactose levels vary according blood glucose, somatic cells count and energy availability for physiological processes. In the literature, rarely has been found greater lactose concentration caused by feed intake, becoming very important the results found in this work. The diet energy concentration and consumption rate determine energy intake, which limit milk yield. Dairy cows in early lactation has marked increased of nutrient requirements to support milk production. Support milk lactose synthesis in the mammary gland is the one of responsible for increase of nutrients requirements. In this period, the glucose demands increases 2 times more than during late gestation. Propionate is converted to glucose in the liver and it will be support lactose synthesis in the mammary gland. Propionate supplementation in this work provided better energetic supply ...

RESUMO:A pecuária de corte brasileira tem sido marcada por intensas transformações, resultantes da aplicação de técnicas modernas de produção, da utilização dos cruzamentos entre raças, e das exigências do mercado consumidor. O desempenho do período pré-desmama é importante por se tratar do primeiro resultado de produtividade animal e a classificação e tipificação das carcaças possibilitam enquadrá-las em diferentes classes e, assim, direcioná-las a diferentes mercados. O objetivo deste trabalho foi comparar o desempenho pré-desmama e características de carcaças entre dois grupos genéticos: Nelore (NE), e ½ sangue Angus-Nelore (F1), os quais foram abatidos sem castração e suplementados a pasto do nascimento ao abate. Foram tomados, ao acaso, 36 animais sendo 18 machos da raça Nelore (NE) e 18 machos oriundos do cruzamento industrial entre Nelore e Angus, machos (F1), sendo todos submetidos ao mesmo manejo e abatidos sem castração, com idade aproximada de 20 meses. Durante o processo de abate, as carcaças foram classificadas e tipificadas. O grupo F1 foi superior ao grupo NE com diferença significativa referente ao peso ao nascer (p=0,0046), peso ajustado aos 205 dias (p=0,0002), peso ao desmame (p=0,0005), ganho de peso diário entre o nascimento e os 205 dias (p=0,001). Quanto às características de carcaças não houve diferença estatística entre os grupos (p>0,05), sendo que, ambos atingiram a exigência frigorífica para espessura de gordura. Observou-se uma superioridade nos animais F1 quanto ao desempenho pré-desmama, e nota-se a possibilidade de terminar animais inteiros a pasto, com acabamento de carcaça mínimo, desde que bem alimentados. PALAVRAS-CHAVE: Abate. Cruzamento industrial. Desempenho pré-desmama. Machos não castrados. Produtividade. WEIGHT GAIN AND CARCASS CHARACTERISTICS OF NELLORE AND CROSSBREED ANGUS-NELLORECATTLE ON GRAZING SUPPLEMENTATION SCHEME ABSTRACT: The Brazilian beef cattle industry has been marked by dramatic changes resulting from the application of modern production techniques, use of crossbreeding and consumer market requirements. The performance of the pre-weaning period is important because it is the first result of animal productivity, and the evaluation and classification of carcasses enable their categorization into different classes, and thus, their directing to different markets. The objective of this study was to compare the pre-weaning performance and carcass traits between two genetic groups: Nellore (NE) and Angus-Nellore crossbreed (F1), which were slaughtered without castration, receiving grazing supplementation from birth to slaughter. Thirty-six animals were randomly selected, 18 Nelore (NE) and 18 Angus-Nellore crossbreed (F1) animals, all males, submitted to the same management system and slaughtered without castration, with approximate age of 20 months. During the slaughtering process, carcasses were classified and typified. The F1 group was superior to the NE group with significant differences related to birth weight (p = 0.0046), weight adjusted to 205 days (p = 0...

RESUMO Feridas cutâneas lacerantes frequentemente são observadas na espécie equina, onde a perda de massa tecidual e contaminação impossibilitam o fechamento primário, necessitando, portanto, do reparo tecidual por segunda intenção, que por sua vez pode levar a um período longo de convalescência e oneroso, aliado ainda a um potencial de formação de cicatrizes não cosméticas, especialmente em feridas profundas distais nos membros. Características singulares do processo cicatricial na espécie e a aplicação inadvertida de curativos podem contribuir para este quadro. Avanços na compreensão do processo reparativo foram recentemente obtidos, embora muitos aspectos ainda sejam controversos. Objetiva-se, portanto, fazer uma revisão das importantes considerações envolvidas, visando uma maior compreensão dos fatores envolvidos na cicatrização e opções terapêuticas deste processo nesta espécie. PALAVRAS-CHAVE: curativos; inflamação; tecido de granulação exuberante. CONSIDERATIONS IN WOUND DERMAL HEALING IN EQUINE: REVIEW ABSTRACT Deep dermal wounds often are observed in equines, where the tissue loss and contamination preclude the primary closure, requering tissue repear for second

Background:The negative energetic balance of lactating cows that occurs during the few weeks postpartum shifts the hormonal profile of the animal. These alterations may lead to metabolic disturbance as ketosis and lipid infiltration. Hypocalcemia is another metabolic problem that occurs in the peripartum period, it is characterized by the reduction in blood levels of calcium (Ca 2+ ) near birth. Blood parameters illustrates the nutritional status of milking cows. The serum levels of glucose, β-hydroxybutyrate (BHB) and cholesterol are parameters that reveal liver condition and it is very important for the metabolism of milking cows. The objective of this study was to evaluate three additives in the form of a calcium salts on blood parameters of lactating cows. Materials, Methods & Results:Two Latin square 4x4 were used, whereas one comprehended of early lactation cows and the other of mid lactation cows. Animals of 2nd and 3rd parity were used only. Parity was distributed evenly among groups. The trial consisted of 4 groups with 4 treatments as follow: T1: 300 g of calcium acetate, T2: 200 g of calcium propionate, T3: 200 g of calcium salts of fatty acids, and T4: control without any calcium additive. Blood samples were collected for analysis of serial calcium, glucose, β-hydroxybutyrate (BHBA) and cholesterol. The calcium levels were higher in T1 than T3 in early lactation. There was no significant difference of glucose levels between groups. Groups T1 and T2 had lower amounts of BHBA. Cholesterol was higher in T3 and T1 in the early lactation and just in T3 was higher in the mid lactation. Discussion: Adjust the Ca 2+ flow due to high feed consumption and milk production near birth is a big challenge for milking cows due to the difficulties to maintain normal serial levels of Ca 2+ in the early lactation. The lower serial levels of Ca 2+ in the group supplemented with calcium salts of fatty acids is due to its physical characteristics that reduces its effects on ruminal microbiota and also reduced absorption of fatty acids in intestine. The evaluation of total cholesterol can be a parameter to judge the productive capacity of milking cows, because it demonstrates the capacity of corporal fat mobilization and ingestion of energy to produce milk. An increase of total cholesterol in cows supplemented with calcium salts of fatty acids is justified by the higher intake of fatty acids in the feed containing fat, which leads to a greater lipid metabolism in blood. As the literature has limited information about calcium acetate, it is believed that the animals supplemented with calcium acetate showed higher levels of cholesterol because the acetate is converted to Acetyl coenzime A, it is the basis for cholesterol biosynthesis in lactating cows. The BHBA can be considered as an indicator of negative energetic balance due to its correlation between energetic demand and energy reserves. As propionate is produced by ruminal fermentation and is the principal source for gluconeogenesis in peripartum cows, it lowered level o...

Natural products can be used as complements or as alternatives to synthetic drugs. Eugenia uniflora and Tropaeolum majus are natives of Brazil and have antimicrobial, anti-inflammatory, and antioxidant activities. This study aimed to develop a film-forming system (FFS) loaded with plant extracts with the potential for treating microbial infections. E. uniflora and T. majus leaf extracts were prepared and characterized, and the individual and combined antioxidant and antimicrobial activities were evaluated. The FFS was developed with different concentrations of polyvinylpyrrolidone (PVP) and polyvinyl alcohol (PVA) and analyzed for physicochemical characteristics. The combination of extracts showed a superior antioxidant effect compared to the individual extracts, justifying the use of the blend. FFS prepared with 4.5% PVA, 4.5% PVP, 7.81% E. uniflora extract, and 3.90% T. majus extract was adhesive, lacked scale formation, presented good malleability, and had a suitable pH for topical application. In addition, the viscosity at rest was satisfactory for maintaining stability; water solubility was adequate; skin permeation was low; and the antimicrobial effect was superior to that of the individual extracts. Therefore, the developed FFS is promising for the differentiated treatment of skin lesions through topical application.