The complement-mediated thrombotic microangiopathy (TMA), also known as atypical hemolytic uremic syndrome (aHUS), is rare and potentially fatal, presenting as TMA and dysfunction/endothelial edema secondary to diffuse disruption of a fluid phase alternating complementary pathways. We report a case of a young woman with postpartum anuric renal failure, TMA and normal levels of AD-AMTS13 with partial clinical improvement after plasmapheresis, in which treatment with eculizumab led to the complete reversal of the clinical manifestations. Our work includes a brief literature review on the diagnosis and management of TMA in puerperium.

Tuberculosis (TB) is a highly prevalent disease in our country, eventually, most with atypical clinical presentations. We report a case of a young patient with prolonged fever and portal hypertension with clinical and histological diagnosis of granulomatous hepatitis, TB improved after treatment with anti-TB regimen. Then we have a brief literature review on the topic.