P atients requiring dialysis for chronic kidney disease comprise a high risk to public health (1), and need for this treatment precluded patients from being able to comply with COVID-19 isolation measures during the pandemic (2). Studies have reported high COVID-19 mortality rates among these patients, but such studies have been scarce in Latin America (3-5). We contrasted clinical and epidemiologic characteristics and outcomes between chronic dialysis (CD) patients and the general population to evaluate COV-ID-19 dynamics during the first year of the pandemic in Argentina. The StudyWe designed an observational, analytic, retrospective, nationwide study that included data from all COVID-19 cases reported to the National Health Surveillance System (SNVS 2.0 ) during epidemiologic weeks (EW) 10/2020 (March 1-7, 2020) through 08/2021 (February 21-27, 2021). COVID-19 cases in CD patients included all cases in persons on dialysis treatment at the time of COVID-19 diagnosis. On March 1, 2021, we downloaded data from an SNVS 2.0 database that included COVID-19 cases reported through EW 08/2021. Notifications provided demographic, clinical, and epidemiologic data; we