The main objective of the research project was to define PLM strategy in the process of developing lower limb prostheses sockets. The present study used different reference framework for PLM strategy configuration. This research was carried out to define the socket design development process by implementing virtual technologies, low-cost additive manufacturing and PLM strategy. The strategy definition was focused on the first three lifecycle stages: ideation, definition, conceptualization and process areas such as product requirements, configuration and changes, product design, product manufacturing and testing. Workflows, activities and roles were subsequently defined with a collaborative work scheme in PLM. This study was intended to meet quality standards and good practices during the product development process, manage resources in an efficient way, integrate technologies, and improve information management as well as communication between all the stakeholders. Finally, the research will allow a future implementation of this strategy in case studies with the aim of comparing traditional socket fabrication processes with the proposed PLM strategy. The study is proposed for the design of lower limb socket development process. A strategy will be set in order to develop transtibial and transfemoral socket cases. This comparison will make it possible to analyse the results obtained from the product development process in aspects such as time, product quality and information management.