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The determination of dynamic crack resistance curves from single specimen fracture tests requires information about the crack advance during the experiment. Here, attention is focused on crack resistance curves for nodular cast iron based on experimental data from instrumented Charpy tests. In order to estimate the actual crack length a key curve method (KCM) is employed. On the other hand, the Charpy impact tests were realized numerically using finite element calculations in conjunction with a continuum damage model (CDM) to simulate ductile crack growth. The parameters of the CDM model were determined from the experimental data of single specimen fracture tests. Equivalence between the experimental and the numerical realization of a fracture test was ensured by validating the predictions of the numerical simulations by means of low blow fracture tests. Comparison between the crack advance predicted by the numerical simulations and the results obtained using the proposed KCM shows a sufficiently well agreement with the actual crack length. Furthermore, crack resistance curves obtained from single specimen tests using A. Emrich · U. Michael Mühlich (B) · M. Kuna either standard estimation schemes in conjunction with the KCM or numerical simulations are compared with the predictions based on low blow fracture tests.