Advance cardiac imaging techniques such as three-dimensional (3D) printing technology and engineering tools have experienced a rapid development over the last decade in many surgical and interventional settings. In presence of complex cardiac and extra-cardiac anatomies, the creation of a physical, patient-specific model is useful to better understand the anatomical spatial relationships and formulate the best surgical or interventional plan. Although many case reports and small series have been published over this topic, at the present time, there is still a lack of strong scientific evidence of the benefit of 3D models and advance engineering tools, including virtual and augmented reality, in clinical practice and only qualitative evaluation of the models has been used to investigate their clinical use.Patient specific 3D models can be printed in many different materials including rigid, flexible and transparent materials, depending on their application. To plan interventional procedure, transparent materials may be preferred in order to better evaluate the device or stent landing zone. 3D models can also be used as an input for augmented and virtual reality application and advance fluido-dynamic simulation, which aim to support the interventional cardiologist before entering the cath-lab.The aim of this chapter is to present an overview on how 3D printing, extended reality platforms and the most common computational engineering methodologiesfinite element and computational fluid dynamicsare currently used to support percutaneous procedures in congenital heart disease (CHD), with examples from the scientific literature.
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